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Prebiotic Acne Therapy 90-Day Regimen

Perricone MD Acne Relief Prebiotic Acne Therapy is a simple, comprehensive system that works with your surface skin’s natural microbiome to safely, gently & effectively treat & prevent the most troublesome acne, while restoring & maintaining a healthy skin balance, for clearer, blemish-free skin. This powerful 2-step regimen is clinically proven to be non-irritating & will not strip or over-dry skin.

Gentle & Soothing Cleanser (6 fl oz / 177 mL)

Step 1 in your regimen. Use both day & night for fighting acne-causing bacteria. The non-foaming formula thoroughly cleanses, reduces excess oil, unclogs pores, removes dead skin cells & eliminates debris without irritating sensitive, acne-prone skin. Ultra-fine sucrose supports a healthy surface skin microbiome, yet rinses off quickly & easily, while squalane hydrates without making skin look or feel greasy.

Calming Treatment & Hydrator (2 fl oz / 59 mL)

Step 2 in your day or morning regimen after cleansing. This lightweight lotion glides onto skin to gently kill acne-causing bacteria, while nourishing with essential hydration. Lactic & succinic acids support a healthy surface skin microbiome for a clearer, more radiant complexion, while citrulline & squalane fight irritation, nourish, hydrate, soothe & visibly reduce redness.

Retinol Treatment & Moisturizer (2 fl oz / 59 mL)

Step 2 in your night regimen after cleansing. The lightweight yet nourishing formula absorbs instantly to control excess oil & helps to heal blemishes while you sleep without over-drying the skin. The powerful combination of retinol, citrulline & niacinamide helps to accelerate surface skin exfoliation & renewal, visibly calm skin & reduce redness, while gently & visibly erasing imperfections overnight.

What It Does

  • Thoroughly cleanses, reduces excess oil, unclogs pores.
  • Eliminates debris without irritating sensitive, acne-prone skin.
  • Gently kills acne-causing bacteria.
  • Hydrates, soothes and visibly reduces redness.
  • Helps to heal blemishes while you sleep without over-drying the skin.

What To Expect

Texture: Varies

Consistency: Varies

Scent: Fragrance-free

Understand the science and benefits behind creating a healthy microbiome and balanced skin.

The science behind Acne Relief is our prebiotic approach, a system that adapts to your skin’s unique microbiome to target troublesome acne. Using naturally occurring prebiotics, Acne Relief helps your skin fight back against acne without disrupting its natural balance. The result? An effective defense against acne-causing bacteria that promotes a clear, blemish-free complexion.

Below are some of the key ingredients in Acne Relief behind our prebiotic approach:

Sucrose is made from ultra-fine sugar and is a mild exfoliant that helps unclog pores and remove excess dirt and oil without over-drying or stripping skin. Sucrose helps support a healthy skin microbiome by encouraging good bacteria. It rinses off quickly and easily, making it ideal for gentle yet effective cleansing.

Citrulline, first discovered in watermelon, is an alpha-amino acid that visibly calms skin for a clearer, more even-looking complexion. Nourishing and soothing, it is an ideal way to counteract the drying effect of anti-acne ingredients.

Lactic & Succinic Acids are short chain fatty acids help quickly shrink blemishes by working alongside salicylic acid to attack acne-causing bacteria and encourage good bacteria necessary for a healthy microbiome. They also provide gentle yet effective exfoliation for smoother, more even-looking skin.

Niacinamide, also known as Vitamin B3, is found in foods such as tomatoes. This skin-clearing powerhouse helps to gently and visibly erase imperfections, unclog oily pores, and minimize the redness and uneven tone that can be left behind after breakouts by improving skin’s moisture barrier.

Squalane is found naturally in the human body but also can be derived from olive oil. It hydrates skin without making it look or feel greasy. This lightweight hydration is ideal for oil and acne prone skin as it helps maintain optimal hydration without clogging pores or causing blemishes.

Salicylic Acid is a beta-hydroxy acid and is considered the best non-prescription treatment for acne and oil-prone skin. It quickly and effectively exfoliates and removes dead skin which can clog pores and cause breakouts. Because it is oil-soluble, salicylic acid is easily absorbed for targeted, more effective treatment.

Retinol is and ultra-powerful, non-prescription Vitamin-A derivative that helps prevent breakouts by unclogging pores and accelerating surface skin exfoliation and renewal. Unique slow-release carrier system helps preserve this unstable ingredient and calm skin.

Gentle & Soothing Cleanser

Active ingredient: Salicylic Acid 2.0%.

Inactive Ingredients: Glycerin, Sodium Cocoyl Isethionate, Ethylhexyl Palmitate, Silica Cetyl Sil- ylate, Sucrose, Squalane, Polyacrylamide, Water/ Aqua/Eau, Caprylyl Glycol, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol

Calming Treatment & Hydrator

Active ingredient: Salicylic Acid 0.5%.

Inactive Ingredients: Water/Aqua/Eau, SD Alco- hol 40-B, Glycerin, C12-15 Alkyl Lactate, PVP, Di- methicone, Polysorbate 20, Citrulline, Squalane, Lactic Acid, Succinic Acid, Polyacrylamide, Dimeth- icone/Vinyl Dimethicone Crosspolymer, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Retinol Treatment & Moisturizer

Active ingredient: Salicylic Acid 0.5%.

Inactive Ingredients: Water/Aqua/Eau, SD Alcohol 40-B, Glycerin, Dicaprylyl Ether, Niacinamide, Cit- rulline, Arginine, Methyl Gluceth-20, Cetearyl Alco- hol, Carbomer, Xanthan Gum, Tocopheryl Acetate, Retinol, Citric Acid, Sodium Hydroxide, Disodium EDTA, PEG-20 Methyl Glucose Sesquistearate, PEG-100 Stearate, Glyceryl Stearate, Methyl Glu- cose Sesquistearate, Polysorbate 20, Phenoxy- ethanol, Sodium Benzoate, Potassium Sorbate

 

Brand:
Perricone MD
Directions:

Gentle & Soothing Cleanser - Step 1: Day & Night

Lather a quarter-sized amount in hands & gently massage onto damp skin. Rinse thoroughly with warm water. For best results, follow with ACNE RELIEF Calming Treatment & Hydrator in the morning & ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

Calming Treatment & Hydrator - Step 2: Day

Shake well. Apply a thin, even layer to skin in the morning. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser.

Retinol Treatment & Moisturizer - Step 2: Night

Shake well. Apply a thin, even layer to skin in the evening. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser.

Volume:
10 fl. oz

Prebiotic Acne Therapy 90-Day Regimen

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USD 89.0

MSRP $125.00

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Spend $75 to receive an On-The-Go Duo (value $49)
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Free gift with $75 purchase
Spend over $75 for a complimentary gift.

Spend $75 to receive an On-The-Go Duo (value $49)
Spend $125 and receive a Deluxe On-The-Go kit (value $141)
Spend $200 to receive the Ultimate On-The-Go Kit (value $186)
Only one gift per order. While stock lasts.

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Perricone MD Acne Relief Prebiotic Acne Therapy is a simple, comprehensive system that works with your surface skin’s natural microbiome to safely, gently & effectively treat & prevent the most troublesome acne, while restoring & maintaining a healthy skin balance, for clearer, blemish-free skin. This powerful 2-step regimen is clinically proven to be non-irritating & will not strip or over-dry skin.

Gentle & Soothing Cleanser (6 fl oz / 177 mL)

Step 1 in your regimen. Use both day & night for fighting acne-causing bacteria. The non-foaming formula thoroughly cleanses, reduces excess oil, unclogs pores, removes dead skin cells & eliminates debris without irritating sensitive, acne-prone skin. Ultra-fine sucrose supports a healthy surface skin microbiome, yet rinses off quickly & easily, while squalane hydrates without making skin look or feel greasy.

Calming Treatment & Hydrator (2 fl oz / 59 mL)

Step 2 in your day or morning regimen after cleansing. This lightweight lotion glides onto skin to gently kill acne-causing bacteria, while nourishing with essential hydration. Lactic & succinic acids support a healthy surface skin microbiome for a clearer, more radiant complexion, while citrulline & squalane fight irritation, nourish, hydrate, soothe & visibly reduce redness.

Retinol Treatment & Moisturizer (2 fl oz / 59 mL)

Step 2 in your night regimen after cleansing. The lightweight yet nourishing formula absorbs instantly to control excess oil & helps to heal blemishes while you sleep without over-drying the skin. The powerful combination of retinol, citrulline & niacinamide helps to accelerate surface skin exfoliation & renewal, visibly calm skin & reduce redness, while gently & visibly erasing imperfections overnight.

What It Does

  • Thoroughly cleanses, reduces excess oil, unclogs pores.
  • Eliminates debris without irritating sensitive, acne-prone skin.
  • Gently kills acne-causing bacteria.
  • Hydrates, soothes and visibly reduces redness.
  • Helps to heal blemishes while you sleep without over-drying the skin.

What To Expect

Texture: Varies

Consistency: Varies

Scent: Fragrance-free

Understand the science and benefits behind creating a healthy microbiome and balanced skin.

The science behind Acne Relief is our prebiotic approach, a system that adapts to your skin’s unique microbiome to target troublesome acne. Using naturally occurring prebiotics, Acne Relief helps your skin fight back against acne without disrupting its natural balance. The result? An effective defense against acne-causing bacteria that promotes a clear, blemish-free complexion.

Below are some of the key ingredients in Acne Relief behind our prebiotic approach:

Sucrose is made from ultra-fine sugar and is a mild exfoliant that helps unclog pores and remove excess dirt and oil without over-drying or stripping skin. Sucrose helps support a healthy skin microbiome by encouraging good bacteria. It rinses off quickly and easily, making it ideal for gentle yet effective cleansing.

Citrulline, first discovered in watermelon, is an alpha-amino acid that visibly calms skin for a clearer, more even-looking complexion. Nourishing and soothing, it is an ideal way to counteract the drying effect of anti-acne ingredients.

Lactic & Succinic Acids are short chain fatty acids help quickly shrink blemishes by working alongside salicylic acid to attack acne-causing bacteria and encourage good bacteria necessary for a healthy microbiome. They also provide gentle yet effective exfoliation for smoother, more even-looking skin.

Niacinamide, also known as Vitamin B3, is found in foods such as tomatoes. This skin-clearing powerhouse helps to gently and visibly erase imperfections, unclog oily pores, and minimize the redness and uneven tone that can be left behind after breakouts by improving skin’s moisture barrier.

Squalane is found naturally in the human body but also can be derived from olive oil. It hydrates skin without making it look or feel greasy. This lightweight hydration is ideal for oil and acne prone skin as it helps maintain optimal hydration without clogging pores or causing blemishes.

Salicylic Acid is a beta-hydroxy acid and is considered the best non-prescription treatment for acne and oil-prone skin. It quickly and effectively exfoliates and removes dead skin which can clog pores and cause breakouts. Because it is oil-soluble, salicylic acid is easily absorbed for targeted, more effective treatment.

Retinol is and ultra-powerful, non-prescription Vitamin-A derivative that helps prevent breakouts by unclogging pores and accelerating surface skin exfoliation and renewal. Unique slow-release carrier system helps preserve this unstable ingredient and calm skin.

Gentle & Soothing Cleanser

Active ingredient: Salicylic Acid 2.0%.

Inactive Ingredients: Glycerin, Sodium Cocoyl Isethionate, Ethylhexyl Palmitate, Silica Cetyl Sil- ylate, Sucrose, Squalane, Polyacrylamide, Water/ Aqua/Eau, Caprylyl Glycol, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol

Calming Treatment & Hydrator

Active ingredient: Salicylic Acid 0.5%.

Inactive Ingredients: Water/Aqua/Eau, SD Alco- hol 40-B, Glycerin, C12-15 Alkyl Lactate, PVP, Di- methicone, Polysorbate 20, Citrulline, Squalane, Lactic Acid, Succinic Acid, Polyacrylamide, Dimeth- icone/Vinyl Dimethicone Crosspolymer, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate

Retinol Treatment & Moisturizer

Active ingredient: Salicylic Acid 0.5%.

Inactive Ingredients: Water/Aqua/Eau, SD Alcohol 40-B, Glycerin, Dicaprylyl Ether, Niacinamide, Cit- rulline, Arginine, Methyl Gluceth-20, Cetearyl Alco- hol, Carbomer, Xanthan Gum, Tocopheryl Acetate, Retinol, Citric Acid, Sodium Hydroxide, Disodium EDTA, PEG-20 Methyl Glucose Sesquistearate, PEG-100 Stearate, Glyceryl Stearate, Methyl Glu- cose Sesquistearate, Polysorbate 20, Phenoxy- ethanol, Sodium Benzoate, Potassium Sorbate

 

Brand:
Perricone MD
Directions:

Gentle & Soothing Cleanser - Step 1: Day & Night

Lather a quarter-sized amount in hands & gently massage onto damp skin. Rinse thoroughly with warm water. For best results, follow with ACNE RELIEF Calming Treatment & Hydrator in the morning & ACNE RELIEF Retinol Treatment & Moisturizer in the evening.

Calming Treatment & Hydrator - Step 2: Day

Shake well. Apply a thin, even layer to skin in the morning. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser.

Retinol Treatment & Moisturizer - Step 2: Night

Shake well. Apply a thin, even layer to skin in the evening. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser.

Volume:
10 fl. oz

Customer Reviews

Overall Rating : 4.38 / 5 (587 Reviews)
  • 384 5 star reviews
  • 111 4 star reviews
  • 47 3 star reviews
  • 22 2 star reviews
  • 23 1 star reviews
See all reviews
 

Top Customer Reviews

Where reviews refer to foods or cosmetic products, results may vary from person to person. Customer reviews are independent and do not represent the views of The Hut Group.

Hate it.

2 stars are only because the cleanser does a great job at removing makeup and actually cleaning the face. But I had a horrible experience with the kit and the other products. I used these products for a month and a half and my skin looks and feels horrible, worse than it ever has. The products made my skin dry, sensitive, and full of acne. At the end of 1.5 months I cannot take how uncomfortable I feel and I am throwing them away.

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ehhh

I've been using this for almost a week and i can see some difference but not much. My skin isn't as bad but I just want to get rid of what I have. Although it's making my face peel and i'm not sure if that's normal? i do have done irritated stops on my face as well :( i think this is just too strong.

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This product is the TRUTH

I found out about this product through a YouTube commercial and instantly purchased it... I won't lie I was desperate to try ANYTHING so I instantly purchased the product.. not even 60 days into the kit and my acne started clearing up tremendously, and I've never loved my skin so much.

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I want to buy it for my daughter but we cant afford it

I think it is going to be good on her face her look bad she got a lot of pimples and black spot

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Not Effective

I really have this a chance. I started using the product around the middle to end of May. Today is Sept. 5th and I have not noticed the acne clearing up. I have used it faithfully everyday. The acne may look nice for a day, but then it comes back the next & I also get more in other areas.

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I will buy this product again and again.

Obsessed. I've been using these products for the past month and my skin has never been better.

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I would buy again

Love the products I see a more clear skin thanks

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I love this product

I love this product, very simple. I have extremely oily skin and this works great for me. I don't use any extra moisturizer in the summer. My skin cleared up so far and also texture / discoloration improving. I love the packaging and that they are serums.

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I would not buy this kit again

I have combination skin that is acne-prone along my jawline and chin. I am going to break it down into the three products in the kit. I have been using the Probiotic Acne Therapy Regimen since June 23 (so roughly 4 weeks now) Gentle & Soothing Cleanser This cleanser feels like a combination of a cleansing balm (oily) and a silicone product. After leaving it on my skin for around 30 seconds, my skin begins to tingle (borderline almost sting). I found that using a gentler foam cleaner to remove this cleanser has dramatically reduce skin irritation. I've never used a cleanser with this consistency, so points on creativity I suppose. Calming Treatment & Hydrator (AM) I found this produce to be leave my face feeling sticky and tingly. In addition, I was under the impression that with this kit, the Hydrator would result in the lack of need of an AM moisturizer. This Hydrator to be moisturizing enough for my skin. I suggest mixing the hydrator in with either a light weight AM moisturizer or in combination with a serum and an oil. Retinol Treatment & Moisturizer (PM) While this product is definitely thicker than the AM Hydrator, it is still not enough to moisturize. Like the Hydrator, it leaves my skin feeling sticky and a bit tacky. It feels like the product sticks to my face rather than penetrating my skin barrier. When I started using the kit, it seemed like my skin was very dewy; however, as I continued to use the kit, I realized that it was my own skin producing more oils to compensate for the lack of moisture in either Step 2 products. In addition, this kit has not been proven to be beneficial to my skin texture. All in all, I have not seen a reduction in acne (in fact, I have more acne and in areas of my face where I have never broke out prior). I will not return the product because customers are responsible for the return shipment costs. After I finish this kit, I will be switching skin regimens.

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Ecstatic About Smooth Even Skin

The acne kit and the pore minimizing toner are definitely a game changer for me. By day 4 of using as instructed, I felt and saw a significant difference In my skin. I have suffered for the past couple of years clusters of under ground black heads on my checks forehead, nose, and chin. It bothered me that my make up would magnify the bumpy texture. I changed my diet, make up brand, brushes, wearing no make up, and used anti aging skincare. nothing worked for me. I didn't realize that at my age 34 yrs old that I needed acne relief. My skin is now smooth, pores are minimized, the under ground pimples practically gone, my foundation and primer sets and wears on my skin perfectly. I can positively say I am in love with the appearance of my skin and Dr Perricone's products.

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