Dr. Perricone’s Legacy Ingredients
After over a decade of scientific research, Dr. Nicholas Perricone published his book, “The Wrinkle Cure.” This New York Times bestseller outlined a revolutionary breakthrough that revealed his Three-Tier Philosophy, the secret to preventing visible signs of aging:
Tier 1: Anti-inflammatory diet
Tier 2: Nutritional supplements
Tier 3: Advanced topical skincare
The main message? “You can look your best, feel your best and enjoy beautiful skin and optimum health every day of your life, provided you start right now,” Dr. Perricone wrote. “And you don’t need expensive, invasive plastic surgery to do it.”
To this day, Dr. Perricone’s extensive research and pioneering Three-Tier Philosophy are admired and cited by endless medical professionals, including fellow dermatologists Dr. Gabriella Vasile and Dr. Claire Wolinsky. “Dr. Perricone was truly ahead of his time with his innovative approach to beauty from the inside-out and outside-in,” Dr. Vasile shares.
While tiers 1 and 2 prioritize health from the inside-out, tier 3 is all about doing so from the outside-in. This tier is powered by science-backed topicals that are clinically proven to reveal a healthy, youthful-looking you.
Today, we’re shining a spotlight on Dr. Nicholas Perricone’s legacy ingredients that make this possible. “They’re gentle, all-natural, non-invasive — and best of all, they work,” he writes.
Vitamin C Ester
To start, you may be wondering what an “ester” is and, to keep it simple, it’s a compound derived from an acid and an alcohol. In the case of our proprietary Vitamin C Ester, it’s the result of combining L-ascorbic acid (basic vitamin C) and palmitic acid (a fatty acid). This “C ester,” Dr. Perricone discovered, was non-acidic and, therefore, completely non-irritating. As a result, our signature Vitamin C Ester delivers all the supercharged brightening and smoothing benefits of traditional vitamin C in a more potent, highly stable and less abrasive manner. Additionally, since Vitamin C Ester is fat-soluble, it is more easily absorbed for maximum antioxidant benefits. In turn, it promotes the appearance of collagen-rich skin by visibly smoothing, brightening and minimizing discoloration over time.
Alpha-Lipoic Acid (ALA)
Deemed “nature's most powerful antioxidant” by Dr. Perricone himself, ALA is a natural molecule found in every cell of the human body. It helps neutralize free radicals and protects against oxidative stress that can cause skin damage. In other words, this age-defying, water- and fat-soluble antioxidant helps shield our skin against environmental aggressors. This makes it great for visibly reducing lines, wrinkles, enlarged pores, breakout scars, dullness, under-eye bags and puffiness.
DMAE
Naturally produced by the human brain, DMAE supports skin’s ability to keep itself visibly tight. When applied topically, it’s easily and quickly absorbed to help visibly sculpt, lift and firm while visibly minimizing pore size, supporting skin’s barrier and protecting against drying environmental aggressors. It works nicely with other ingredients to address a wider range of concerns for an overall improved appearance. Vitamin C Ester and ALA, for example, work flawlessly with DMAE in skincare — together, they can address nearly every visible sign of aging, significantly removing lines, wrinkles, discoloration and loss of firmness.
Acyl-Glutathione
Glutathione, AKA the human body’s main antioxidant, is becoming increasingly trendy in topical skincare, particularly when it comes to addressing visible signs of aging. According to Dr. Wolinsky, this is thanks, in part, to its versatility: “Whether a consumer struggles with pigmentation, wrinkles, creases, dullness or the like, they love that it can help correct and prevent their existing skin woes.” This “master antioxidant” helps boost the benefits of fellow antioxidants in skincare. When it comes to topical application, our patented acyl-glutathione (a fat-soluble form of glutathione) promotes improved absorption and stability for optimal benefits.
Shop by ingredient on our site to begin incorporating our signature sciences into your daily skincare regimen. The results will truly blow you away.
