Advanced Serum Concentrate

(1459) Read Reviews
Advanced Serum Concentrate - Perricone MD
  • Advanced Serum Concentrate


Advanced Serum Concentrate - Perricone MD
(1459) Read Reviews
One jar that does it all. A multi-tasking powerhouse, this advanced face serum concentrate promotes the 9 most visible signs of healthy, youthful-looking skin. Targets and dramatically improves loss of radiance, uneven texture, uneven tone, discoloration, redness, enlarged pores, fine lines, wrinkles and loss of firmness. Read More
$149.00 134.10
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Additional Information

Product Details

What It Is

A multi-tasking powerhouse that uses a proprietary liquid crystal delivery system for faster and deeper penetration of key ingredients into skin’s surface. This advanced serum concentrate targets skin’s individual needs to deliver visible and personalized results.

Packed with powerhouse ingredients, including copper tripeptides to improve the appearance of firmness and elasticity, Vitamin C Ester to reduce the look of dark spots and radiance and omegas 3, 6 and 9 to promote smoother, more supple-looking skin.

What It Does
  • Smooths the appearance of lines, wrinkles and uneven texture.
  • Visibly corrects discoloration, redness and uneven skin tone.
  • Lifts and firms skin’s appearance.
  • Transforms dullness into beautiful, youthful radiance.
What To Expect

Serum Concentrate


Lightweight, fast-absorbing



Clinical Results

100% showed a significant improvement in lines & wrinkles.

97% showed a significant improvement in pore size.

Consumer Results

87% saw more radiance and improved texture.

83% saw more even skin tone.

81% saw less discoloration and less redness.

79% felt firmer skin.


Vitamin C Ester: Supercharged Brightening & Smoothing

A more potent, highly stable and less irritating form of antioxidant-rich Vitamin C, Vitamin C Ester gives the appearance of collagen-rich skin by visibly smoothing, brightening and minimizing discoloration over time. Unlike traditional Vitamin C, Vitamin C Ester is fat-soluble and easily absorbable for maximum antioxidant benefits.

Copper Tripeptide

A powerful, naturally occurring complex with three amino acids helps repair dry skin for a dramatically firmer, smoother, younger-looking complexion. This amino acid trio is highly absorb-able and helps protect against environmental aggressors.

Omegas 3, 6, and 9

Found in walnuts and flax seeds, these pro-fatty acids help visibly plump and increase radiance over time by strengthening skin’s moisture barrier and improving its ability to retain water. Omegas 3 & 6 are essential yet do not occur naturally in the body.


Water/Aqua/Eau, Glycerin, Isopropyl Palmitate, Cetearyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Butylene Glycol, Phosphatidylcholine, Tetrahexyldecyl Ascorbate, Dimethyl MEA, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-3, Tyrosine, Glycolic Acid, Helianthus Annuus (Sunflower) Seed Oil, Magnesium Aspartate, Zinc Gluconate, Rosmarinus Officinalis (Rosemary) Leaf Extract, Copper Gluconate, Sodium Hyaluronate, Retinyl Palmitate, Echium Plantagineum Seed Oil, Hydrolyzed Myrtus Communis Leaf Extract, Copper Tripeptide-1, Dimethicone, Disodium EDTA, Carbomer, Ceteareth-20, Cyclopentasiloxane, Caprylyl Glycol, Cetearyl Alcohol, Cyclohexasiloxane, Polysorbate 20, Zea Mays (Corn) Oil, Phenoxyethanol, Sorbic Acid



After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.


I have several Dr. P products, serums, etc. however, I am curious as to how to combine them. Such as, cold plasma and the acyl-glutathione if I let each soak in, then add moisturizer? It seems a lot. So far, I've been trading days, one day I do one product and trade the next day. And now I bought more products for the morning and have the same issue. I suppose I was hoping for a way to layer.


Ideally you'll use the Cold Plasma as a base layer and then follow with the Acyl-Glutathione. Finish with your moisturizer and/or solar protection and you've got a good anti-aging regimen.


Do I need moisturizer in addition to cold plasma +?


Yes; Cold plasma Plus Face is used as an anti-aging treatment before moisturizer.


How does Cold Plasma Plus Face differ from the "old" Cold Plasma.

Debbie Payne

Cold Plasma Plus is the new unscented version of Cold Plasma with a more concentrated lighter-weight texture and new actives such as Copper Tripeptides and Vitamin C Ester. The original Cold Plasma formulation has a silkier more fortifying texture, yet it is still lightweight. It includes marine algae with Omega 3 fatty acids to nourish the skin.


55 years old. My major skin concerns are combo skin, pores, some sagging, slight 11s and slight forehead creases, and sun spots. Please tell me the order of application for am and pm routines for these products, and do I need to remove or add anything else. Not addressing neck and eye concerns. Cold plasma +, Amine Face Lift, Face Firming Activator, Acyl glut deep crease, Vit C Ester serum. Using a.m. SPF and Renova 3-4x/week (pm). Do I need to add a pore treatment, DMAE pads, Concentrated Restorative Treatment, Neuropeptide Night Therapy or any other product? Please recommend a moisturizer as well. Thanks so much for your help! :-)


Cold Plasma will always be your first step, followed by Acyl-Glutathione Deep Crease Serum, and High Potency Face Firming Activator or High Potency Amine Face Lift. Everyone's skin is unique, and we recommend you call the helpful customer care team for more specific guidance based on your concerns. Our toll-free number is 1-888-823-7837.


I's this really on clearance? Is it going away? It's the only thing that helps my red irritated skin. Please don't take it away!


Hello, it is not being discontinued it was just on sale.


Testing, testing, 123... now is the time for all good men to come to the aide of their country... the lazy brown dog, sits and barks at the postal carrier.


Testing response..


Tested, received, answered, saved and published....


Can I combine this product and use prior to applying Pericone MD Nourishing Moisturizer? Or it's best to use each alone


We recommend using them together for the best results. Apply Cold Plasma Plus Face first.


In what order do i apply my Cold plasma face and my neuropeptide facial cream and my Neuropeptide Firming Moisturizer? I also have the Neoropeptide Night Cream. Please let me know the order of what goes first please. Thank you.


Cold Plasma Plus Face will be the first step, followed by the Neuropeptide Facial Cream in the mornings, Neuropeptide Night Cream in the evenings, and the last step will be the Neuropeptide Firming Moisturizer.


Is there an SPF in any of the Cold Plasma products?


Hello, we have SPF 30 in our Photo Plasma, our No Foundation makeup, the Face Finishing Moisturizer tint, the Daily Brightening Moisturizer and SPF 25 in the Cold Plasma Neck & Chest.







I have just finished my 7 day samples and I want another 7 days immediately!! It really helped my skin, felt like it toned and cleared up my complexion no end, I am a smoker and I honestly felt it looked a lot brighter after only 7 days

Katie k




Lovely product. Went on well. Could see a difference.

Alison B


Glow and radiance giver


I have noted my skin to be highly smooth and radiant with this 7 day sample packet that I was given. My skin is glowy and smooth. This really helps to even out the skin, lessen pores and even out creases in the skin. Use this for gradual improvement to the skin over atleast a two month period to truly appreciate the results. This product is worth every penny.



Love, love, love this product


I have been a fan of Dr Perricone for many years but recently bought the new Cold Plasma Face and am absolutely delighted with it. You need very little of this product & your skin completely absorbs the cream and leaves the skin looking firm, supple, plump and glowing. Everyone has commented at how great my skin looks and it feels very soft & hydrated .... no mean feat at 61!

Beauty junkie



It does what it says!...


I love this product. My 65 year young skin is very happy. Toned, smooth, discoloration to a bare minimum. The only reaon I have only 4 stars--- the price.


Pittsburgh PA


Luxury product


Really great product, gave it to my mum to try out and she loved it, really started to notice a difference in her skin

Gabriella B


A product that works!


I was very dubious on this product. As I am with many. However, I notice a small difference in a small space of time. So I bought this product, as it definitely works.

Jane B


I love this product


Amazing !! Left my skin incredible so healthy soft and glowing

Kelly k




I love everything Perricone, and this didn't disappoint. So so good!

Monica I


Pericone convert


Love me beauty got me into Pericone some time ago and I love their skin products. They are light to apply and you feel they are doing you good.

Gillian W



4.2 1459


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