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Vitamin C Ester is Perricone MD's proprietary, fat-soluble form of vitamin C — delivering the brightening, discoloration-fighting benefits of traditional vitamin C without the irritation or instability. Independent research shows it absorbs into skin up to seven times more effectively than L-ascorbic acid, the water-soluble vitamin C found in most other products.
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WHAT IS IT?

Vitamin C Ester is a unique combination of L-ascorbic acid (traditional vitamin C) and palmitic acid, a fatty acid derived from palm oil. That combination is what makes the difference: unlike traditional vitamin C, which is water-soluble, Vitamin C Ester is fat-soluble, allowing it to penetrate skin more easily and resist the breakdown that plagues most vitamin C formulas.

Traditional vitamin C is notoriously difficult to formulate with — it's acidic, prone to irritation, and loses potency quickly once a product is opened, often within six months. Dr. Perricone developed Vitamin C Ester specifically to solve this: all of the brightening, antioxidant, and collagen-supporting benefits of vitamin C, in a form skin can actually use.

Vitamin C Ester is one of Perricone MD's five Signature Sciences — ingredients Dr. Perricone identified for their proven ability to visibly transform how skin looks and feels.

1. Deep Absorption

Its fat-soluble structure lets Vitamin C Ester move past the skin's surface far more efficiently than water-soluble vitamin C.

2. Antioxidant defense

Once absorbed, it neutralizes free radicals from UV exposure and pollution before they can accelerate visible aging.

3. Discoloration fade

It works to inhibit excess pigment production, gradually fading the look of dark spots and uneven tone.

4. Visible result

Skin appears brighter, smoother, and more even-toned, with continued improvement over consistent use.

Formulas with Vitamin C Ester