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Twenty years of research have yielded our most advanced and comprehensive reparative treatment. This unique combination of concentrated, patented sciences tackles the look of advanced photo-damage and discoloration, rough, dull texture, fine lines and wrinkles. Over time skin is visibly transformed and complexion looks noticeably brighter, smoother and clearer.

What It Does

  • Improves the appearance of skin’s elasticity and suppleness.
  • Dramatically smooths the look of uneven texture, fine lines and wrinkles.
  • Visibly corrects the look of severe photo-damage

What To Expect

Due to the science and compounds used in our products the feel and scent may vary.

Texture: Serum

Consistency: Lightweight

Scent: Natural

*This product is free from gluten, fish, milk, phthalates, parabens, talc, and mineral oil. Cruelty-free and 100% vegan.

CLINICAL RESULTS

84% showed improvement in skin firmness & elasticity*
82% showed reduction in photo damage*
77% showed improvement in lines & wrinkles*
*In a clinical study of 31 women after 8 weeks.

CONSUMER RESULTS

91% agreed skin feels smoother**
89% agreed skin feels softer**
84% agreed texture improved**
**In a consumer study of 100 women after 28 days

Neuropeptides: Uniting Surface Cells to Fight Wrinkles

Powerful, protein-like building blocks offer the ultimate visible antidote to the look of wrinkles, sagging, dullness and discoloration. Neuropeptides support skin’s barrier and hydration via a unique chemical structure.

DMAE: Intensive Firming

Naturally produced by the human brain, DMAE helps visibly lift sagging skin over time. Easily and quickly absorbed, it visibly plumps skin to help support skin’s surface and protect against drying environmental aggressors.

Vitamin C Ester: Supercharged Brightening & Smoothing

A more potent, highly stable and less abrasive form of antioxidant powerhouse vitamin C, Vitamin C Ester gives the appearance of collagen-rich skin by visibly smoothing, brightening and minimizing the look of discoloration over time. Unlike traditional vitamin C, Vitamin C Ester is fat-soluble and easily absorbable for maximum antioxidant benefits.

Ingredients:

Water/Aqua/Eau, C12-15 Alkyl Benzoate, Dimethyl MEA, Butylene Glycol, Citric Acid, Glycerin, Tyrosine, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Isopropyl Palmitate, Dimethicone, Simmondsia Chinensis (Jojoba) Seed Oil, Tetrahexyldecyl Ascorbate, Phosphatidylcholine, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Hydrolyzed Oat Protein, Ceramide NG, Zinc Gluconate, Magnesium Aspartate, Copper Gluconate, Rutin, Sodium Carboxymethyl Beta-Glucan, Phaseolus Lunatus (Green Bean) Seed Extract, Carbomer, Disodium EDTA, BHT, Triethanolamine, Caprylyl Glycol, Propylene Glycol, Ammonium Acryloyldimethyltaurate/VP Copolymer, PEG-10 Phytosterol, Polysorbate 20, Cetyl Hydroxyethylcellulose, Glyceryl Polymethacrylate, Tribehenin, Phenoxyethanol, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Imidazolidinyl Urea, Fragrance/Parfum, Benzyl Alcohol

Range:
Neuropeptide
Volume:
1 oz / 30ml, 2oz / 59ml
Directions:

After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.

Brand:
Perricone MD

Neuropeptide Smoothing Facial Conformer

A neuropeptide-rich treatment that minimizes the appearance of fine lines and wrinkles while enhancing skin's radiance and elasticity. This powerful peptide brightening serum tackles dull skin, advanced photo-damage, skin discoloration, and more.

Purchase options
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USD 325.0
Starting at $325.00
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Twenty years of research have yielded our most advanced and comprehensive reparative treatment. This unique combination of concentrated, patented sciences tackles the look of advanced photo-damage and discoloration, rough, dull texture, fine lines and wrinkles. Over time skin is visibly transformed and complexion looks noticeably brighter, smoother and clearer.

What It Does

  • Improves the appearance of skin’s elasticity and suppleness.
  • Dramatically smooths the look of uneven texture, fine lines and wrinkles.
  • Visibly corrects the look of severe photo-damage

What To Expect

Due to the science and compounds used in our products the feel and scent may vary.

Texture: Serum

Consistency: Lightweight

Scent: Natural

*This product is free from gluten, fish, milk, phthalates, parabens, talc, and mineral oil. Cruelty-free and 100% vegan.

CLINICAL RESULTS

84% showed improvement in skin firmness & elasticity*
82% showed reduction in photo damage*
77% showed improvement in lines & wrinkles*
*In a clinical study of 31 women after 8 weeks.

CONSUMER RESULTS

91% agreed skin feels smoother**
89% agreed skin feels softer**
84% agreed texture improved**
**In a consumer study of 100 women after 28 days

Neuropeptides: Uniting Surface Cells to Fight Wrinkles

Powerful, protein-like building blocks offer the ultimate visible antidote to the look of wrinkles, sagging, dullness and discoloration. Neuropeptides support skin’s barrier and hydration via a unique chemical structure.

DMAE: Intensive Firming

Naturally produced by the human brain, DMAE helps visibly lift sagging skin over time. Easily and quickly absorbed, it visibly plumps skin to help support skin’s surface and protect against drying environmental aggressors.

Vitamin C Ester: Supercharged Brightening & Smoothing

A more potent, highly stable and less abrasive form of antioxidant powerhouse vitamin C, Vitamin C Ester gives the appearance of collagen-rich skin by visibly smoothing, brightening and minimizing the look of discoloration over time. Unlike traditional vitamin C, Vitamin C Ester is fat-soluble and easily absorbable for maximum antioxidant benefits.

Ingredients:

Water/Aqua/Eau, C12-15 Alkyl Benzoate, Dimethyl MEA, Butylene Glycol, Citric Acid, Glycerin, Tyrosine, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Isopropyl Palmitate, Dimethicone, Simmondsia Chinensis (Jojoba) Seed Oil, Tetrahexyldecyl Ascorbate, Phosphatidylcholine, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Hydrolyzed Oat Protein, Ceramide NG, Zinc Gluconate, Magnesium Aspartate, Copper Gluconate, Rutin, Sodium Carboxymethyl Beta-Glucan, Phaseolus Lunatus (Green Bean) Seed Extract, Carbomer, Disodium EDTA, BHT, Triethanolamine, Caprylyl Glycol, Propylene Glycol, Ammonium Acryloyldimethyltaurate/VP Copolymer, PEG-10 Phytosterol, Polysorbate 20, Cetyl Hydroxyethylcellulose, Glyceryl Polymethacrylate, Tribehenin, Phenoxyethanol, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Imidazolidinyl Urea, Fragrance/Parfum, Benzyl Alcohol

Range:
Neuropeptide
Volume:
1 oz / 30ml, 2oz / 59ml
Directions:

After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.

Brand:
Perricone MD

Customer Reviews

Overall Rating : 4.72 / 5 (78 Reviews)
  • 68 5 star reviews
  • 5 4 star reviews
  • 1 3 star reviews
  • 1 2 star reviews
  • 3 1 star reviews
See all reviews
 

Top Customer Reviews

Where reviews refer to foods or cosmetic products, results may vary from person to person. Customer reviews are independent and do not represent the views of The Hut Group.

Love this product!

Great product!! Try to order as often as I can afford it.

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Miracle in a bottle

Using it once daily. This amazing product helps your skin and it’s appearance in every way. Smooths, plumps, brightens and softens your skin to absolute perfection. Love it !! ✨

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I can never live without this product

It really helps heal any blemishes or anything that comes on my skin. It brightened my skin so I wore less makeup!

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The product stinks ..

Product smells funny..

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This Really Works!

I know this is expensive, but for me it is a no brainer. In 1 month, it has evened my skin tone, shrunk the pores on my nose and chin, and helped firm the skin on my face. I will definitely repurchase. Oh! Forgot to mention that I don't use moisturizer due to very oily skin, and this has helped to calm this issue, too.

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My favorite of all my favorite Perricone products

I can SEE the difference when I use it...

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i would buy this product again

Just love it.

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Love, love, love

I have used this product for many years. I love it as much now as I did years ago.

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Worth it

Between the Smoothing Facial Conformer and Firming Evening Repair I've noticed a significant improvement in my skin. It looks a lot more youthful.

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I will stay on product rest of my life

I first found this product on a shopping network. Purchased on a special price that was affordable. Did not do auto pay and regretted it. I have been without this product for a couple years and decided my skin was looking awful and repurchased along with some other items. This is a wonderful product and my skin looks fab. Will not be without it again. I'm on auto pay. I'm 72 and look much younger and my skin is so beautiful. Thank you

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