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Powerful day and night serum formulated with Dr. Perricone’s next generation polyamine technology to deliver a visibly dramatic lifting effect, leaving the skin looking smooth and radiant. Supports the skin’s moisture barrier and visibly improves skin plumpness, strength, cushion, bounce and resiliency.
What It Does
- Delivers a visibly dramatic lifting effect
- Visibly improves the look of skin's plumpness, strength, cushion, bounce and resiliency
What To Expect
Due to the unique technology of our Encapsulated Retinol, the formula may feel slightly gritty upon initial application. This is normal. As the product is massaged into the face, the encapsulation will break and the retinol will absorb easily into the skin.
Texture: Serum
Consistency: Lightweight
Scent: Natural, fresh, aromatic
After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.
Clinical Results
89% showed improvement in skin redness and the appearance of skin radiance & brightness*
78% showed improvement in the appearance of skin tone*
76% showed improvement in skin firmness*
*In a clinical study with 38 women after 56 days.
Consumer Results
89% agreed skin looked smoother**
88% saw smoother fine lines**
87% felt more resilient skin**
85% felt firmer skin and saw improved skin texture**
85% agreed skin looked healthier**
84% noticed skin elasticity appeared improved and felt dull skin appeared brighter**
84% saw a reduction in the appearance of wrinkles**
82% saw an improvement in skin tightness**
80% felt stronger skin and noticed surface imperfections minimized**
79% agreed skin looked more radiant & felt firmer**
77% agreed skin felt lifted**
76% noticed skin felt plump & skin tone was more even**
75% felt the appearance of pores minimized**
**In a consumer study with 104 women after 28 days.
Polyamine Growth Factor: Supports Healthy-Looking Skin & Youthful Radiance
An endogenous molecule utilized by nearly every living thing on Earth, polyamine growth factor improves the feel of skin elasticity and helps promote the look of youthful, collagen-rich and visibly firmer skin by replenishing moisture. Skin produces smaller quantities of growth factors with age, often linked to the most visible signs of aging like fine lines, wrinkles, loss of elasticity and uneven texture.
Eggshell Membrane: The Gatekeeper
The thin, water-soluble layer that lines an eggshell, eggshell membrane supports the skin’s moisture barrier and provides the skin with a youthful texture and radiance by improving the feel of elasticity over time. Known to protect the egg white and yolk, this thin layer is also used topically to nourish and protect the skin.
Encapsulated Retinol: Accelerated Skin Renewal
A stabilized form of retinol, this ultra-powerful, non-prescription vitamin A derivative replenishes the look of thin, collagen-depleted skin by accelerating surface skin exfoliation and renewal. The microcapsules fracture when applied to the skin, facilitating a highly effective, controlled release of potent ingredients.
Ingredients:
Water/Aqua/Eau, Butylene Glycol, Heptyl Undecylenate, Lecithin, Alcohol Denat., Polymethyl Methacrylate, Niacinamide, Pentaerythrityl Adipate/ Caprate/Caprylate/Heptanoate, Phosphatidylcholine, Ascorbyl Palmitate, Hydrolyzed Egg Shell Membrane, Tricaprylin, Retinol, Tocopherol, BHT, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dipropylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Stearic Acid, Caprylyl Glycol, Glyceryl Stearate, PEG-100 Stearate, Spermidine, Sodium Polyacrylate, Phenoxyethanol, Fragrance/Parfum, Limonene, Linalool, Hydroxycitronellal, Citronellol, Benzyl Alcohol, Geraniol
- High Potency
- Perricone MD
- 2 fl.oz / 59ml
Frequently Bought Together



Total Price: $210.00
Add both to cart
High Potency Growth Factor Firming & Lifting Serum
Powerful day and night serum to visibly lift and improve skin plumpness, cushion, bounce and resiliency.
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$135.00
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4 instalments of $33.75 with Klarna Learn more
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4 installments of $33.75 with afterpay Learn more
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4 installments of $33.75 with zip Learn more
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Powerful day and night serum formulated with Dr. Perricone’s next generation polyamine technology to deliver a visibly dramatic lifting effect, leaving the skin looking smooth and radiant. Supports the skin’s moisture barrier and visibly improves skin plumpness, strength, cushion, bounce and resiliency.
What It Does
- Delivers a visibly dramatic lifting effect
- Visibly improves the look of skin's plumpness, strength, cushion, bounce and resiliency
What To Expect
Due to the unique technology of our Encapsulated Retinol, the formula may feel slightly gritty upon initial application. This is normal. As the product is massaged into the face, the encapsulation will break and the retinol will absorb easily into the skin.
Texture: Serum
Consistency: Lightweight
Scent: Natural, fresh, aromatic
After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.
Clinical Results
89% showed improvement in skin redness and the appearance of skin radiance & brightness*
78% showed improvement in the appearance of skin tone*
76% showed improvement in skin firmness*
*In a clinical study with 38 women after 56 days.
Consumer Results
89% agreed skin looked smoother**
88% saw smoother fine lines**
87% felt more resilient skin**
85% felt firmer skin and saw improved skin texture**
85% agreed skin looked healthier**
84% noticed skin elasticity appeared improved and felt dull skin appeared brighter**
84% saw a reduction in the appearance of wrinkles**
82% saw an improvement in skin tightness**
80% felt stronger skin and noticed surface imperfections minimized**
79% agreed skin looked more radiant & felt firmer**
77% agreed skin felt lifted**
76% noticed skin felt plump & skin tone was more even**
75% felt the appearance of pores minimized**
**In a consumer study with 104 women after 28 days.
Polyamine Growth Factor: Supports Healthy-Looking Skin & Youthful Radiance
An endogenous molecule utilized by nearly every living thing on Earth, polyamine growth factor improves the feel of skin elasticity and helps promote the look of youthful, collagen-rich and visibly firmer skin by replenishing moisture. Skin produces smaller quantities of growth factors with age, often linked to the most visible signs of aging like fine lines, wrinkles, loss of elasticity and uneven texture.
Eggshell Membrane: The Gatekeeper
The thin, water-soluble layer that lines an eggshell, eggshell membrane supports the skin’s moisture barrier and provides the skin with a youthful texture and radiance by improving the feel of elasticity over time. Known to protect the egg white and yolk, this thin layer is also used topically to nourish and protect the skin.
Encapsulated Retinol: Accelerated Skin Renewal
A stabilized form of retinol, this ultra-powerful, non-prescription vitamin A derivative replenishes the look of thin, collagen-depleted skin by accelerating surface skin exfoliation and renewal. The microcapsules fracture when applied to the skin, facilitating a highly effective, controlled release of potent ingredients.
Ingredients:
Water/Aqua/Eau, Butylene Glycol, Heptyl Undecylenate, Lecithin, Alcohol Denat., Polymethyl Methacrylate, Niacinamide, Pentaerythrityl Adipate/ Caprate/Caprylate/Heptanoate, Phosphatidylcholine, Ascorbyl Palmitate, Hydrolyzed Egg Shell Membrane, Tricaprylin, Retinol, Tocopherol, BHT, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Dipropylene Glycol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Cetearyl Alcohol, Stearic Acid, Caprylyl Glycol, Glyceryl Stearate, PEG-100 Stearate, Spermidine, Sodium Polyacrylate, Phenoxyethanol, Fragrance/Parfum, Limonene, Linalool, Hydroxycitronellal, Citronellol, Benzyl Alcohol, Geraniol
- High Potency
- Perricone MD
- 2 fl.oz / 59ml
Frequently Bought Together



Total Price: $210.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to foods or cosmetic products, results may vary from person to person. Customer reviews are independent and do not represent the views of The Hut Group.
Stocked up!
I am, literally, afraid to run out of this product! My skin is so firm, taut and free of fine lines and wrinkles, even at 71. No one guesses my age at over 60. I use every single drop of the bottle, including what's in the pump, and never miss a day. I always order a bottle way ahead of running out. It's a blessing when it's on sale. The new shipping method is wicked fast! I ordered Wednesday and received it Friday! Very happy!
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My Staple Serum
This has been a staple in my skin care routine for years. It’s helped to keep my skin hydrated and smooth. I apply over entire face, after applying my target area serums (eye serum, deep crease serum) … then finish up with a moisturizer. Can’t go wrong with this serum.
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Holy grail!
This definitely changed my skin routine game ! It made my skin more even , hydrated and lifted. It does exactly what it states . Love it !Â
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Holy grail!
In love with the growth factor! Use it after my chia oil and it transformed my skin! My best friend actually asked me what I was using and the difference is truly amazing. I will never be without it, everyone needs this !Â
Top Reviewer
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Holy grail!
This product absolutely changed my skin , tone and firmness. I received a sample at first and realized that I can’t live without this product! I get so many compliments on my skin, I honestly can’t live without it!Â
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Perfume terrible
Beware of the heavy perfume. It makes my eyes water. Wasted my money. Very disappointed in the brand.
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WOW
I am a 24 year old female that has struggled with acne, scarring, discoloration, and dullness for YEARS. When I tell you I have tried everything, I mean EVERYTHING. My mom gave me this serum as part of a travel kit she got as a gift. I am obsessed with it now and would recommend it to anyone wanting to brighten up their skin and give it a new life. I’ve never seen results from a product like I have this one. I had fully accepted that skincare was a scam and gave up all hope. Now I understand that you get what ya pay for!! 🥲
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I will never use anything else
This is a must have in my routine. I will never use anything else. Really helped me with fine lines.Â
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High Potency Growth Firming & Lifting Serum
I have been using this product for over two years and will not be without.  It is a product that does what it says.  I think of it as  food for the face.
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I'd buy this before food!
If I had to choose between buying food and this serum, the serum wins. I'm 70 and have ZERO wrinkles. I have been using PMD since 1998 or so, that's why! My skin is firm, tight, and lifted and, since I also use the brightening 30 SPF moisturizer, no sun spots, either. People stop me on the street to say how beautiful my skin is, as do the makeup artists when I'm on set. It's for reals!
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