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A nutrient-packed moisturizer with a rich, velvety texture that deeply moisturizes yet absorbs quickly without any residual grease or stickiness. Delivers the optimal nourishment to strengthen and replenish skin’s moisture barrier, keeping vital nourishment in and environmental aggressors out. Skin appears plump, firmed, lifted and smooth.
What It Does
- Delivers optimal nourishment to help address dry, tight skin.
- Visibly improves etched creases making them appear more shallow.
- Minimizes the appearance of skin imperfections and imparts a beautiful radiance.
What To Expect
Due to the science and compounds used in our products the feel and scent may vary.
Texture: Cream
Consistency: Velvety-rich
Scent: Natural, aromatic rose
*This product is free from soy, nuts, gluten, fish, milk, corn, phthalates, sulfates, parabens, talc, and mineral oil. Cruelty-free and 100% vegan.
Massage onto cleansed face and neck using a gentle upward motion. Use morning and evening. For best results, apply after your favorite Perricone MD serum, serum concentrate or facial cream.
Consumer Results*
Overall Skin Condition
87% felt skin was deeply moisturized*
84% felt more supple skin*
83% saw revitalized skin with a healthy glow*
81% felt skin was plumped*
77% noticed skin was visibly perfected*
Advanced Claims
76% saw an improvement in firmness, tightness & fragile texture*
75% saw an improvement in skin elasticity & wrinkles*
74% noticed an improvement in skin crepiness*
70% saw an improvement in deep creases*
70% felt skin was lifted*
*In a consumer study of 102 women after 28 days.
Acyl-Glutathione: The Master Antioxidant
Comprised of 3 amino acids, glutathione is the body’s main antioxidant and as part of a comprehensive skincare regimen can help to reduce the look of wrinkles and creases by replenishing fragile skin. Natural levels of this essential building block deplete over time, but topical application can help skin appear smoother and more youthful.
Vitamin F Blend: Ultimate Moisture Barrier Protection
Flax, chia and macadamia seed oils work over time to restore suppleness and create a healthy glow by intensely moisturizing and improving skin’s moisture barrier. Essential, yet not naturally found in the human body.
Ingredients:
Water/Aqua/Eau, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, PEG-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum (Linseed) Seed Oil, Macadamia Ternifolia Seed Oil, Phospholipids, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Fragrance/Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool
- Essential Fx Acyl-Glutathione
- 1 fl.oz / 30ml
- Perricone MD
Frequently Bought Together



Starting at $290.00
Add both to cart
Essential Fx Acyl-Glutathione Rejuvenating Moisturizer
A nutrient-packed moisturizer to deeply moisturize, visibly firm, lift and smooth skin's appearance.
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4 instalments of $26.25 with Klarna Learn more
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4 installments of $26.25 with afterpay Learn more
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4 installments of $26.25 with zip Learn more
SAVE 35% WITH CODE: EFXACYL
Offer Valid though 10/06/2023 11:59 p.m. Pacific Time or while supplies last. Offer cannot be combined with other discounts or applied to past or future purchases. Other restrictions, exclusions or terms may apply.
Offer Valid though 10/06/2023 11:59 p.m. Pacific Time or while supplies last. Offer cannot be combined with other discounts or applied to past or future purchases. Other restrictions, exclusions or terms may apply.
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A nutrient-packed moisturizer with a rich, velvety texture that deeply moisturizes yet absorbs quickly without any residual grease or stickiness. Delivers the optimal nourishment to strengthen and replenish skin’s moisture barrier, keeping vital nourishment in and environmental aggressors out. Skin appears plump, firmed, lifted and smooth.
What It Does
- Delivers optimal nourishment to help address dry, tight skin.
- Visibly improves etched creases making them appear more shallow.
- Minimizes the appearance of skin imperfections and imparts a beautiful radiance.
What To Expect
Due to the science and compounds used in our products the feel and scent may vary.
Texture: Cream
Consistency: Velvety-rich
Scent: Natural, aromatic rose
*This product is free from soy, nuts, gluten, fish, milk, corn, phthalates, sulfates, parabens, talc, and mineral oil. Cruelty-free and 100% vegan.
Massage onto cleansed face and neck using a gentle upward motion. Use morning and evening. For best results, apply after your favorite Perricone MD serum, serum concentrate or facial cream.
Consumer Results*
Overall Skin Condition
87% felt skin was deeply moisturized*
84% felt more supple skin*
83% saw revitalized skin with a healthy glow*
81% felt skin was plumped*
77% noticed skin was visibly perfected*
Advanced Claims
76% saw an improvement in firmness, tightness & fragile texture*
75% saw an improvement in skin elasticity & wrinkles*
74% noticed an improvement in skin crepiness*
70% saw an improvement in deep creases*
70% felt skin was lifted*
*In a consumer study of 102 women after 28 days.
Acyl-Glutathione: The Master Antioxidant
Comprised of 3 amino acids, glutathione is the body’s main antioxidant and as part of a comprehensive skincare regimen can help to reduce the look of wrinkles and creases by replenishing fragile skin. Natural levels of this essential building block deplete over time, but topical application can help skin appear smoother and more youthful.
Vitamin F Blend: Ultimate Moisture Barrier Protection
Flax, chia and macadamia seed oils work over time to restore suppleness and create a healthy glow by intensely moisturizing and improving skin’s moisture barrier. Essential, yet not naturally found in the human body.
Ingredients:
Water/Aqua/Eau, Ethylhexyl Palmitate, Glycerin, Dimethicone, Cetearyl Alcohol, Glyceryl Stearate, Polysorbate 60, Palmitoyl Glycine, S-Palmitoylglutathione, Tetrahexyldecyl Ascorbate, PEG-100 Stearate, Ribose, Lactic Acid, Linum Usitatissimum (Linseed) Seed Oil, Macadamia Ternifolia Seed Oil, Phospholipids, Polyglyceryl-10 Stearate, Ethylhexylglycerin, Salvia Hispanica Seed Oil, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Rosmarinus Officinalis (Rosemary) Leaf Extract, Tetrasodium Glutamate Diacetate, Sodium Hydroxide, Polyacrylamide, Sodium Acrylates Copolymer, Polysilicone-11, Hydrogenated Polyisobutene, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Fragrance/Parfum, Citronellol, Hydroxycitronellal, Limonene, Linalool
- Essential Fx Acyl-Glutathione
- 1 fl.oz / 30ml
- Perricone MD
Frequently Bought Together



Starting at $290.00
Add both to cart
Customer Reviews
Top Customer Reviews
Where reviews refer to foods or cosmetic products, results may vary from person to person. Customer reviews are independent and do not represent the views of The Hut Group.
Essential FX Acyl-Glutathione
Love the smell of this product when first put it on !!! Noticeable difference in deeper wrinkles that were in my neck & decollete area. Very pleased with the difference this product makes.
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Ordering Again Right Now!
If you are looking for a great face cream that doesn't take forever to make a difference on wrinkles this is it. I really can't say enough about it and can't say anything negative.
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🌻🦋 Moisturizers & ME 🦋🌻
Love the feel on my skin particularity the T zone area of my face.
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Nice Moisturizer
It's a nice moisturizer. It's hydrates my skin. Calms down my skin and it protects my skin barrier! I like the scent but it's way to strong!! Why you need to add so much perfume in a face cream? I have no idea. I like the rejuvenating moisturizer. But I'm not buying it again because of the to strong scent. It's hard to recommend with so much perfume in it! Sorry Dr. Perricone, you can do it better.
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best moisturizer
I absolutely love this moisturize, i use it twice a day in the am and pm. Makes my skins so soft and hydrated, I hesitate to try anything new. Highly recommend this moisturizer!!
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Results you can see...quickly!
I bought the Essential FX Acyl Glutathione Rejuvenating Moisturizer a month ago, and the results are absolutely amazing! My deep crease in between my eyes is almost non-existent, my skin tone is much more even, the loss of volume is improving and my skin is much firmer. I use this cream in the morning, and use the Acyl Glutathione cream for evening before bed. These are powerful weapons in my arsenal of anti-aging. I've been using Perricone MD products for over 20 years, and people have consistently told me I look at least 15 years younger. I won't be without this cream...ever!
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Really enjoyed outcomes
Increased hydration and bright even tone over several months of use- additional product used: Cold Plasma+
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Luxurious and nourishing
The Essential Fx Acyl-Glutathione Rejuvenating Moisturizer does exactly what it claims. Skin feels calm, hydrated and supple. No break out
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It is Working
I'm So glad that I made this purchase. The Essential Fx Acyl-Glutathione Rejuvenating Moisturizer is Definitely "Plumping" some areas out. An it is very moisturizing. Sinks in Quickly Too. I also use the Deep Crease Serum, which is Working even better now that its paired with the Moisturizer ❤!!
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Love this product
It's light, but moisturizing, and it also firms.
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