Smoothing Facial Conformer

Smoothing Facial Conformer - Perricone MD
  • Smoothing Facial Conformer


Smoothing Facial Conformer - Perricone MD
A neuropeptide-rich treatment that minimizes the appearance of fine lines and wrinkles while enhancing skin’s radiance and elasticity. This powerful peptide brightening serum tackles dull skin, advanced photodamage, skin discoloration, and more. Read More
$325.00 292.50
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Product Details

What It Is

Twenty years of research have yielded our most advanced and comprehensive reparative peptide skin brightening serum. A unique combination of concentrated, patented key sciences visibly corrects severe photodamage (sun damage), uneven texture and tone, as well as fine lines and wrinkles.

Neuropeptides offer the ultimate visible antidote to wrinkles, sagging and dullness, while DMAE helps visibly lift sagging skin. Our proprietary Vitamin C Ester visibly smooths, brightens and minimizes skin discoloration. Skin is visibly transformed to boost skin elasticity and reveal a brighter, smoother and clearer-looking complexion.

What It Does
  • Improves the appearance of skin’s elasticity and suppleness.
  • Minimizes the appearance of deep lines and wrinkles.
  • Reversing the signs of photo damage.
What To Expect

Due to the science and compounds used in our products the feel and scent may vary.








DMAE: Instant Firming

Naturally produced by the human brain, DMAE helps visibly lift sagging skin over time. Easily and quickly absorbed, it visibly plumps skin to help support skin's surface and protect against drying environmental aggressors.

Vitamin C Ester: Supercharged Brightening & Smoothing

A more potent, highly stable and less irritating form of antioxidant-rich Vitamin C, Vitamin C Ester gives the appearance of collagen-rich skin by visibly smoothing, brightening and minimizing discoloration over time. Unlike traditional Vitamin C, Vitamin C Ester is fat-soluble and easily absorbable for maximum antioxidant benefits.

Neuropeptides: Uniting Surface Cells to Fight Wrinkles

Powerful, protein-like building blocks offer the ultimate visible antidote to wrinkles, sagging, dullness, and discoloration. Neuropeptides encourage surface skin cells to work together via a unique chemical structure.


Water/Aqua/Eau, C12-15 Alkyl Benzoate, Dimethyl MEA, Butylene Glycol, Citric Acid, Glycerin, Tyrosine, Glyceryl Stearate, PEG-100 Stearate, Cetyl Alcohol, Isopropyl Palmitate, Dimethicone, Simmondsia Chinensis (Jojoba) Seed Oil, Tetrahexyldecyl Ascorbate, Phosphatidylcholine, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Hydrolyzed Oat Protein, Ceramide NG, Zinc Gluconate, Magnesium Aspartate, Copper Gluconate, Rutin, Sodium Carboxymethyl Beta-Glucan, Phaseolus Lunatus (Green Bean) Seed Extract, Carbomer, Disodium EDTA, BHT, Triethanolamine, Caprylyl Glycol, Propylene Glycol, Ammonium Acryloyldimethyltaurate/VP Copolymer, PEG-10 Phytosterol, Polysorbate 20, Cetyl Hydroxyethylcellulose, Glyceryl Polymethacrylate, Tribehenin, Phenoxyethanol, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Imidazolidinyl Urea, Fragrance/Parfum, Benzyl Alcohol.



After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.


I currently use Serum Prep. If purchased, would the Facial Conformer be used instead of the Prep?


Hello, the Serum Prep is a wonderful anti-aging toner. You would use that first and then apply the Smoothing Facial Conforer on top which is a treatment for discoloration, toning & tightening and helping with lines and wrinkles. Follor up with a moisturizer.


hi,this is cream?or serum?


Neuropeptide Facial Conformer is a serum, applied before moisturizing cream.


For the Neuropeptide Facial Cream and the Facial Conformer - what order do you apply in the morning, do you put the facial conformer on first?


Great question. You only need to use the Neuropeptide Facial Conformer once a day. You can put the Facial Cream on top of the Conformer if you like or use one day and one night, follow up with a moisturizer on top if needed.

Perricdone MD Skincare Specialist

I use Ovm, Deep Crease Acyl-Glut, Cold Plasma, Hylo Plasma, Formula15 in the morning and Restorative Concentrate in the evening. I just bought the Conformer and would like to use it three days a week. Would I still use the Acyl-glut, Ovm, and hylo plasm when using the Conformer?


Awesome question! Dr. Perricone recommends using the Neuropeptide Facial Conformer 3 times per week in place of your normal Perricone treatments. What that means is on the days you use the Conformer omit the other treatments; and only use the following with the Conformer: Cleanser, Eye Treatment and Moisturizer.

Perricone MD Skincare Specialist

Is the facial conformer more powerful than the signature reserve?

Newbie 2 perr.

Thank you for contacting Perricone MD. Yes, the Neuropeptide Facial Conformer is the strongest treatment in Dr. Perricone's skin care line and that is why we recommend using this product 3 days a week in place of other Perricone treatments. I hope this is helpful.

Perricone MD Skincare Specialist

In the review, it states "depending on number of WEEKLY a applications, this product can last up to six months" How often should this product be applied? Only weekly?


The Neuropeptide Facial Conformer can be applied 2 to 3 times per week in place of your other treatment products.

Perricone MD Customer Care

Is there any harm in starting to use this product early? I am approaching 30 and am trying to keep my skin looking 20-something for as long as possible! I am very fair and generally have to take good care of my skin due to breakouts and sun damage. I currently use blue plasma, cold plasma, and face finishing moisturiser on a daily basis. Please let me know if this is a product I should consider, or if you have any alternative suggestions. Thanks

Aussie fan

Thank you for contacting Perricone MD. No, it is not harmful to start using the products early; they will actually be quite beneficial; they will work as a preventative measure. In other words, using the products early will slow down the aging process and you will be less likely to have wrinkles and sagging skin in the future because you started taking such good care of your skin in your early years. Following a healthy diet and exercise as well as taking Dr. Perricone's supplements is also quite helpful. Happy Holidays!

Perricone MD Skincare Specialist

Hi.I am 50, suffer from mild rosacea causing uneven skin texture and discouloration, widespread capillaries, small underskin pimples. I have combination skin presenting severe sagging cheeks with loss of jaw line definition; the skin is also sagging under my lower eyelids, so as to produce some sort of cross "half-bags" on my upper cheeks. Not too much wrinkles but some fine lines all over the eye area, where there are some very small but annoying fat whiteheads. I have been told to start with the following regimen, in that application order: Nutritive Cleanser, AM: Cold Plasma, Formula 15, Face Finishing Moisturizer, Cold Plasma Sub-D, Blue Plasma Orbital, High Potency Eye Lift, mineral sunscreen 50+. PM: Blu Plasma (every other day), Cold Plasma, Neuropeptide Facial Conformer (on neck too), following as above (except sunscreen, of course). Twice a year, seasonally, two tubes of Vitamin C Ester 15 as sole night treatment before Cold Plasma and other products. Thank you in advance.


Thank you for contacting Perricone MD. The products that were recommended are right on target. The Cold Plasma and Formula 15 are treatments that we normally recommend to our clients with rosacea; and also dress so many other skin care concerns such as: wrinkles, enlarged pores, dryness, redness, discoloration, uneven skin tone, impurities, loss of firmness, loss of smoothness, and loss of radiance. The Vitamin C Ester 15 is an excellent serum that will assist with correcting discoloration as well as tightening and firming the skin and you can't go wrong with the Neuropeptide Facial Conformer. The Neuropeptide products are the strongest treatments in Dr. Perricone's skin care line and will tighten and firm loose skin. I think you are definitely on the right track!

Perricone MD Skincare Specialist

Does this or any other Perricone product offer sun protection? What is the SPF?


The Neuropeptide Facial Conformer does not contain a sunscreen; however, we have quite a few products in our line that contain an SPF and below I am providing a list for your review: Photo Plasma No Foundation Foundation No Foundation Serum No Concealer Concealer No Blush Blush I hope this is helpful.

Perricone MD Skincare Specialist

I am 41 and concerned about deepening lines above my upper lip and around my eyes. I've been using Cold Plasma, Acyl-Glutathione and Acyl-Glutathione Eye Lid Serum with face finishing moisturiser, and haven't seen any improvement. In fact it seems to be getting worse. Is the Neuropeptide series the strongest way to address lip and eye creases or would I be better served with the Acyl-Glutathione Deep Crease Serum? Is there any product that targets upper lip lines specifically? I won't use the lip plumper because it has parabens. Thank you.


I recommend the Neuropeptide Collection, which consists of: NP Facial Conformer NP Eye Contour NP Firming Moisturizer I hope this is helpful.

Perricone MD Skincare Specialist




Awesome product...


I am 63 and look 53...use this lotion every other night and love the results. I use this product with many Perricone MD lotions daily and they all are working. I highly recommend their products...they are costly but DEFINITELY are worth it!!! Pick your poison...cost and effective, or cheap and wrinkles.....


Auburn, CA


Neuropeptide Facial Conformer


I use this product 2 or 3 times a week. It is my favorite of all the Perricone products. Lifts & firms and so easy to apply. I have used Perricone for many years & they are all beneficial.


Little Rock, AR




I have only one word to describe this product... AMAZING!! I don't normally write reviews but felt compelled to write one on this product because it's that good. It is a true game changer. You will LOVE the results. I have. If you are on the fence BUY IT!


San Jose, CA


Can't Live Without......


If there was a such thing as a miracle in a bottle this is it! Since my 1st use I was hooked and religiously use my Neuropeptide Facial Conformer every night. I truly hate being without so I make sure I never run out. My skins appearance has been transformed and is more youthful, toned, supple, and of course firmer. I have used this for a couple years now and even know the sales clerks by name where I shop since it's the only place I can walk in and buy. On my last visit to buy my magic potion they teased me telling me that I should use it only a couple times a week like other customers since I run through bottles faster than any others they have ever know. My response was if I could bathe in it I would.... Thank you Perricone for such a life changing product I truly appreciate it. Smell??? Yes a slight one. But really? Results are what matter to me =-)


Huntington Beach, CA


Yes I would buy this product above any other products


Basically I love this produce even if it's very expensive.




I would deff buy this! It works!


I started using this a month ago an I luv it! It has my skin feeling so soft an smooth its also helped with a red patch of roseacea on my face! Its gone!! I'd deff buy this product an recommend it to all skin types


Hazard, Ky


Warning...Extreme feminine scent!


Warning...unusable for those sensitive to strong scents, especially males! I'm not sure if it works as I couldn't get past the smell, direct to the trash.


Miami, FL


It Really Works


Have been using this Facial Conformer and it just keeps on working. Especially for someone as old as I am.

Big Fan

Ramsey, NJ


I have not found another producto that can compete with NFC.


I am 68 years old, and to me NFC is a fountain of youth. It's been 13 years since I've been using it. For many years I used it once a week. For some other years I increased it to twice a week, and now I have just started using it one other day, and I don't look 68!! This product keeps depression away from me!!! Thank you Dr. Perricone!!!




Fantastic Glow & firmness


I used this product in the evening after blue plasma. My skin has never looked or more importantly felt better! I can see results. As a matter of fact I have a twin sister and she noticed the change in my skin and inquired what I was using. She now is a convert too. WHAT A POWERHOUSE!


oneida, ny


Smoothing Facial Conformer

4.8 38


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