High Potency Classics

Face Firming Serum

Face Firming Serum - Perricone MD
  • Face Firming Serum
  • Face Firming Serum
  • Face Firming Serum
  • Face Firming Serum


Face Firming Serum - Perricone MD
High Potency Classics Face Firming Serum is a powerhouse anti-wrinkle serum that includes the highest potency of Perricone MD's signature sciences. This intense wrinkle serum features alpha lipoic acid to help smooth skin and visibly reduce the length, width and depth of wrinkles. Read More
$99.00 89.10
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Product Details

What It Is

High Potency Classics Face Firming Serum, previously available only through dermatologists, is formulated with the highest potency active ingredients. Considered by devotees to be the best wrinkle serum to help visibly minimize wrinkles. Delivers a luminous, vibrant, fresh complexion.

The unique power of this anti-wrinkle serum lies in its multiple sciences. alpha lipoic acid, a powerful antioxidant, improves the appearance of the depth of a wrinkle. DMAE tackles the length and width of a wrinkle by visibly lifting and firming the look of skin. Hyaluronic acid adds to the multi-tasking power of this wrinkle serum, resulting in an anti-wrinkle serum that is intensely hydrating and exceptionally effective. So potent you may feel a slight tingling after application.

What It Does
  • Minimizes the appearance of the length, width and depth of a wrinkle.
  • Refines the look of enlarged pores.
  • Improves the appearance of skin texture while imparting radiance and glow.
What To Expect

Due to the science and compounds used in our products the feel and scent may vary.






Natural, fresh, aromatic

Consumer Results

97% agreed skin looked healthier.

91% saw a reduction in the appearance of fine lines & wrinkles.

91% agreed skin had a radiant glow.


Alpha Lipoic Acid (ALA): Nature's Most Powerful Antioxidant

A fatty acid found in every cell in the human body, ALA reduces the appearance of lines, wrinkles and enlarged pores over time. Fat and water-soluble, ALA is highly absorbable and works alongside the body's own antioxidant system.

DMAE: Instant Firming

Naturally produced by the human brain, DMAE helps visibly lift sagging skin over time. Easily and quickly absorbed, it visibly plumps skin to help support skin's surface and protect against drying environmental aggressors.

Hyaluronic Acid (HA): Instant All-Day Hydration

An important part of the skin’s natural support structure, topical HA provides essential hydration for visibly plumper skin. A low molecular weight enables HA to effectively penetrate the skin's surface. This powerful substance is more hydrating than any other known skincare ingredient.


Water/Aqua/Eau, Dimethyl MEA, Thioctic Acid, Isopropyl Palmitate, Cetearyl Alcohol, Tyrosine, Glycolic Acid, Dimethyl Isosorbide, Propanediol, Glyceryl Stearate, PEG-100 Stearate, Urea, Phosphatidylcholine, Xanthan Gum, Magnesium Aspartate, Zinc Gluconate, Acetyl Tyrosine, Pyridoxine HCL, Copper Gluconate, Sodium Hyaluronate, BHT, Disodium EDTA, Ceteareth-20, Ammonium Acryloyldimethyltaurate/VP Copolymer, Dimethicone, Caprylyl Glycol, Zinc Sulfate, Phenoxyethanol, Sorbic Acid, Fragrance/Parfum, Citral, Citronellol, Geraniol, Limonene, Linalool.



After cleansing, massage onto face and neck using a gentle upward motion. Wait until fully absorbed and follow with your favorite Perricone MD moisturizer. Use morning and evening.


I see ALA and DMAE listed as 2 ingredients that are supposed to be part of the science of the product but don't see them listed in the ingredients....why?


Hi, great question, the DMAE and the Alpha Lipoic Acid are shown under Dimethyl MEA, which is for the DMAE and ALA is under Thioctic Acid


Hello, the DMAE and the Alpha Lipoic Acid are shown under Dimethyl MEA, which is for the DMAE and ALA is under Thioctic Acid


Hello, the DMAE and the Alpha Lipoic Acid are shown under Dimethyl MEA, which is for the DMAE and ALA is under Thioctic Acid


Hello, I was wondering which specific ingredient of the ingredient list in this product represents the Hyaluronic Acid?


Hello, the Hyaluronic Acid is also known as SodiumHyaluronate.


How is this product different from the High Potency Amine lift serum? They both say they have the same ingredients when reading the descriptions. Please advise the difference between the two. Thanks

Lisa Stock

The High Potency Amine Face Lift contains the actives Vitamin C Ester and DMAE for brightening and firming, and the High Potency Face Firming Activator contains the actives Alpha Lipoic Acid and DMAE for firming and smoothing the texture of the skin.


I have fairly sensitive skin and am in my late twenties, I am using this more as a preventative measure. Will this be OK for my skin? If not what would you recommend for that?


Hi there. We might suggest you start with Cold Plasma - especially as you state your skin is a bit on the sensitive side.. Cold Plasma represents Dr. Perricone's most comprehensive research to date and is the result of five years of development. Formulated with Dr. Perricone's proprietary delivery system, Cold Plasma offers the skin all it needs for optimal health, while helping address the ten visible signs of aging: wrinkles, enlarged pores, dryness, redness, discoloration, uneven skin tone, impurities, loss of firmness, loss of smoothness, and loss of radiance. For your concern - wanting to hold-off the aging process.. PMD

Have any of the ingredients or their proportions changed in the renaming process?


Great question, no, there have been no formulation changes.

In the past I purchased advanced face firming activator. Is this the same product and is now called high potency face firming activator?

Over the hill

Thank you for your question. The Advanced Face Firing Activator is the new High Potency face activator. It is a day time treatment with Alpha Lipoic Acid and DMAE




I am buying this product again


I use this product in the evening, my skin is so very smooth in the morning and has a beautiful glow


Edgewater, NJ


Yes I would buy this product again


I actually wear under my no makeup makeup. My skin looks and feels toned.


Gardiner, Montana


Fountain of Youth!


My must have everyday! When you get to a certain age (over 60) it is hard to find one cream, treatment, moisturizer that does it all, and Perricone High Potency Face Firming Activator is that one product for me. It brings youth back to my face!

Cat lover

North East U.S.




I've used this serum for two months and I have seen no positive result. To be honest, after years of working for plastic surgeons, I don't believe any skincare product that says it will firm my skin. It's not physically possible to achieve the tightening effect that the word "firming" makes me hope for. That said, I expect smoother texture and a more even skin tone. A slightly more supple, "plumped" feel is a bonus. I've gotten those results with serums at higher and lower price points. The serum has an unpleasantly strong herbal/essential oil scent, but it fades quickly, so that wasn't a barrier to using it. It takes a couple minutes to dry before I can apply a moisturizer. That's okay too. It didn' make me break out. I don't want to be one of those women who just says something vague about a product not working, but that's the extent of it: no better, no worse. With the amazingly effective ingredients available today and the cachet of the Perricone brand, that is not good enough. I put in the money, the time and the hope for a realistic improvement that isn't easy to achieve but is possible. It didn't deliver on any promise. I'm a completionist so I'll finish it, but I will not buy it again.






This product is the first one I put on morning and night. It is lightweight yet does so much. Firms my face and softens my complexion . You can add many products over it and it will activate all other ingredients.


Tampa, Fl


Did not work


Daughter got this for me for Christmas with some of there other products. Been using since December my face looks terrible but I thought I would give it a chance. Going back to my old skin products so I can look and feel better about myself




Will buy again & again


I use this product every morning! I love it and the way it feels on my face & neck... I have definitely experienced an overall firming after use......Love it!


Little Rock, AR


I've been using this over 10 years and still love it.


I use this every morning


San Diego


I am a repeat user, just love this product. Very bad smell!


Try to eliminate the very bad odor.


Charlotte, NC


Cannot live without it


I have been using High Potency Face Firming Activator (it called back then Formula15) ever since I was introduced to Perricone MD April 2014. From day one I could see the change. I was 45 and looked old (usually i look 25, so it was a real blow and needed a quick change): my face started going down, pigmentation everywhere...in less than a month, my face was on its way back to the way it was. I am using Perricone MD cleanser, firmer cold plasma (currently moved to Cold Plasma plus) and then High Potency Face Firming Activator Always finish with Photo Plasma morning or Face Finishing Moisturizer at night. High Potency Face Firming Activator - smells great, well absorbed and does the work - keep my face moisturized, helps a great deal with lowering pigmentation and acne level - Highly recommended


San Diego CA


Face Firming Serum

4.5 46


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