Brightening Overnight Treatment

(105) Read Reviews
Brightening Overnight Treatment - Perricone MD
  • Brightening Overnight Treatment
  • Brightening Overnight Treatment
  • Brightening Overnight Treatment
  • Brightening Overnight Treatment
  • Brightening Overnight Treatment


Brightening Overnight Treatment - Perricone MD
(105) Read Reviews
An ultra-restorative treatment that works as the best night cream to dramatically and visibly even skin tone, reduce age spots and improve elasticity over time. Wake up to skin that looks brighter and feels noticeably firmer. Read More
$99.00 89.10
Add to cart options

Additional Information

Product Details

What It Is

One of the best night creams in the collection, this ultra-restorative formula improves elasticity and visibly minimizes visible sun damage and age spots.

Our brightening night cream is formulated with Vitamin C Ester to give the appearance of collagen-rich skin by visibly smoothing and brightening. Glycolic acid instantly exfoliates and hydrates, while amino acids visibly improve skin’s firmness.

What It Does
  • Visibly evens skin tone and improves the appearance of discoloration.
  • Minimizes the appearance of lines and wrinkles.
  • Promotes the natural glow and smoothness of youthful-looking skin.
What To Expect

Due to the science and compounds used in our products the feel and scent may vary.






Fresh & Aromatic


Vitamin C Ester: Supercharged Brightening & Smoothing

A more potent, highly stable and less irritating form of antioxidant-rich Vitamin C, Vitamin C Ester gives the appearance of collagen-rich skin by visibly smoothing, brightening and minimizing discoloration over time. Unlike traditional Vitamin C, Vitamin C Ester is fat-soluble and easily absorbable for maximum antioxidant benefits.

Amino Acids: Build Stronger Skin

Organic compounds that make up 75% of the human body, amino acids hydrate for firmer, smoother looking skin, strengthen surface skin cells, and have been used for a variety of skin conditions.

Glycolic Acid: Superior Exfoliation

An ultra-powerful alpha hydroxy acid (AHA) instantly exfoliates, hydrates, and visibly reduces discoloration. A low molecular weight enables it to penetrate deep into skin's surface where it acts as a highly effective alternative to harsh physical exfoliants.


Water/Aqua/Eau, Tetrahexyldecyl Ascorbate, Isopropyl Palmitate, Tyrosine, Glycolic Acid, Cetearyl Alcohol, Urea, Triethanolamine, Sodium Carboxymethyl Beta-Glucan, Butylene Glycol, Tocopheryl Acetate, Cyclopentasiloxane, Camellia Sinensis Leaf Extract, Dimethicone, Dimethyl MEA, Ascorbyl Palmitate, Sodium Hyaluronate, Allantoin, Bisabolol, Tocotrienols, Pyridoxine HCl, Pantethine, Tocopherol, Citric Acid, Disodium EDTA, BHT, Ceteareth-20, Cyclohexasiloxane, Ethoxydiglycol, Glyceryl Stearate, PEG-100 Stearate, Caprylyl Glycol, Elaeis Guineensis (Palm) Oil, Zinc Sulfate, Phenoxyethanol, Sorbic Acid, Fragrance/Parfum, Benzyl Benzoate.



Massage onto cleansed face and neck in the evening using a gentle upward motion. Wait until fully absorbed, then follow with your favorite Perricone MD moisturizer if necessary.


What is the vit c concentration of this product ? Should it be used everyday ? Can it be used while using lytera or alternating ? Thank you


The concentration is the highest amount that can be added to the formulation while still remaining potent and stable, which is proprietary information. It can be combined with other treatments though we recommend alternating if you have sensitive skin or experience any irritation. For best results we recommend using it nightly.


Hello I'm almost 29 and started to notice my nasolabial folds! Would this be a good treatment to correct and treat them as well as preventing them from getting deeper? Or which product would you recommend? Thank you!


Good question, yes, the Concentrated Restorative Treatment would help with nasal labial folds. The Vitamin C Ester in the Concentrated Restorative Treatment along with the DMAE in this product will lift and firm your skin making the nasal labial folds less evident.

Which of perricon product is not gluten,soy,milk,yeast free? Which of the product is more powerful for brown spots which appeared after berthing? Concentrated Restorative Treatment or the the Vitamin C Ester 15. I have also a problem of enlarged pores.


Thank you for contacting Perricone MD. All of Dr. Perricone's topical products are gluten free except the following: - Face Finishing Moisturizer - No Foundation Foundation 1 - No Foundation Foundation 2 - No Lipstick Lipstick - No Mascara Mascara The most powerful treatment for brown spots would be the Vitamin C Ester 15 and for enlarged pores I recommend Dr. Perricone's Pore Power Duo which consists of the Intensive Pore Minimizer, and the Intensive Pore Treatment. Have a nice day!

Perricone MD Customer Care Specialist

Im confused when reading some of your answers on how to use the concentrated restorative treatment with the vitamin Ester C 15. Can they both be used at night since they both have ester c? and would cold plasma be applied after these?


Great question! Yes, the Concentrated Restorative Treatment and Vitamin C Ester 15 can be used together, and they are both PM treatments. No, the Cold Plasma is always the very 1st Perricone treatment applied both AM & PM. Below I am listing the correct order of application: AM Application- Cleanser, Toner or serum, Cold Plasma, moisturizer last PM Application: Cleanser, Vitamin C Ester 15, Cold Plasma, Concentrated Restorative Treatment and a moisturizer last.

Perricone MD Skincare Specialist

I'm having trouble understanding which products I should be using and how they should follow one another? In the morning I'm using the following listed: 1. High Potency Amine Face Lift (or should I be using Formula 15 or either or?) 2. Face Finishing Moisturizer When do you use the Neuropeptide facial cream? I believe this is to be used right before the moisturizer in the morning. In the evening I'm using the following listed: 1. Blue Plasma 2. High Potency Evening Repair (or should I be using concentrated restorative treatment) I have no questions regarding the neck or eye. Please help me understand which products I should use or which products that I am using that are just over kill


Thank you for contacting Perricone MD. There are five steps to following the Perricone regime and they are: 1. Cleanser 2. Toner or Serum 3. Exfoliant - (PM ONLY) 4. Treatment 5. Moisturizer Both the HP Amine Face Lift and Formula 15 are AM treatments and I recommend alternating the morning of usage; there is no need to layer these 2 treatments. The Neuropeptide Facial Cream is an AM treatment and should be applied first then follow with either HP Amine or Formula 15. The Blue Plasma is a pm exfoliant and should be applied after cleansing and using a toner or serum; once skin is dry apply the HP Evening Repair. The Face Finishing Moisturizer is applied both AM & PM and it is always last after Perricone treatment. If you are not seeing results then you can add the Concentrated Restorative Treatment, its personal preference. We also have an Application Protocol Sheet listed on our website: www.perriconemd.com; simply click at the top of the page on Customer Service, and to the left you will see a drop down menu, click on "Application Protocol". I hope this is helpful.

Perricone MD Skincare Specialist

Should it be used as serum after toner? Or should follow after serum and use it as night cream? Don't know what the right step is.


The Concentrated Restorative Treatment is a pm treatment only. You will apply your Serum prior to the Concentrated Restorative Treatment and then follow with a moisturizer.

I am currently using The Ester C cream, then Blue Plasma, then this cream, then the deep moisturizer in the PM. Is that a suitable way to use the product?


Great question! In using the products you have mentioned, you will first apply the Blue Plasma, as this is a non-acidic daily peel. Then you will follow with the Vitamin C Ester 15, Concentrated Restorative Treatment, and the Deep Moisture Therapy last.

I am 20 years old with sensitive skin and looking to treat acne scars, is this a good product to try?


Thank you for contacting Perricone MD. The product I recommend for scarring would be the Advanced Face Firming Activator. The Advanced Face Firming Activator (AM treatment) provides immediate improvement to the appearance of skin's resilience, tone and texture. Alpha Lipoic Acid and glycolic acid reduce pore size and speed up cell renewal, while reducing the appearance of scarring and discolorations in the skin. Use before your moisturizer and sunscreen. However, this product is in the process of being discontinued and should be available the remainder of 2014; and when this product is no longer available I recommend switching to Formula 15, which is the replacement. I hope this is helpful.

Perricone MD Skincare Specialist

I have this cream, Vit C Ester, HP Evening Repair for night treatment, how to use if I wanna use all those three ?


Thank you for contacting Perricone MD. There are five steps to following the Perricone regime and they are: 1. Cleanser 2. Toner or Serum 3. Exfoliant 4. Treatment 5. Moisturizer The Vitamin C Ester 15 is a PM serum/treatment and should be applied after cleansing and using a toner, then follow with the High Potency Evening Repair and a moisturizer should always be applied last. I hope this is helpful. Happy Holidays!

Perricone MD Skincare Specialist

Can i use this at the same time as high potency evening repair?


Thank you for contacting Perricone MD. The Concentrated Restorative Treatment and the High Potency Evening Repair are both PM treatments and we do not recommend layering one on top of the other; however, if you have both of these treatments to achieve maximum results I recommend alternating the nights of usage. For example: Monday, Wednesday & Friday - Use the High Potency Evening Repair and on the remaining days use the Concentrated Restorative Treatment. A moisturizer should always be applied last. I hope this is helpful.

Perricone MD Skincare Specialist




Really makes my skin look better


I use at bedtime and wake up to better, smoother, softer, moisturized skin. I can tell when I forget to use it.


Eastern Shore, MD


using for 2 weeks and already see a difference


love it but dont love the smell


jupiter, fl


Is my second time I get it


It is very good to unify the tone of the skin and remove stains and discolorations by the sun

Maria E

Santiago, Chile


My new fav from dr. pericone MD


I've only have had this for 3 days now but I am so impressed with this product that I decided to go ahead and do a review... It is 7 a.m. And I am so impressed that I had to go ahead and write my review. My skin is already feeling much softer. My skin Appears to be more plump and I cannot say enough about the texture as well as the tone of my skin. Something I wasn't expecting, and this is a big plus for me.. that pesky deep wrinkle that I have between my eyes.. the one I referred to as the only thing I got from my last marriage... well to my surprise I noticed it is hardly noticeable:-) :-) I am in love with this stuff. I have used dr. Perricone products for many years. I have used other products here and there but always return to my dr. perricone MD people actually make jokes about dr. Perricone being my idol LOL I am 50 years old and would wear bangs just to hide that deep wrinkle I think I'll wear my hair up today:-) thank you dr. perricone

Lei lei

Statesville nc


I love this treatment


I'm a big Perricone fan and won't use any other products. I alternate my night treatments and Concentrate Restorative Treatment is one I often use. I love the texture and ingredients. Dr. Perricone's treatments have taken years off of my age and my skin looks better now at 57 then when I was in my thirties. I hope this product is never discontinued. Thank you, Dr. Perricone. Nothing compares to your skin care line.




I love it


I wikll buy this again


Puyallup wa


I have been using this product for 10 year


I love this product and have been using it since I turned 40. I get compliments on my skin all the time. It's one that I never let run out. It's my secret weapon to keeping my skin looking fresh and youthful!! Great for people dealing with melasma!

Beauty junkie



My Favorite Perricone Product


Luxuriously rich cream that will make your skin look healthy and radiant the next morning. Like using a facial scrub only a hundred times better because it moisturizes too. I use it under one of Perricone's other creams at night and I am constantly getting compliments on my skin. Truly like medicine in a jar.


San Francisco, CA


I love this cream!


This cream is Restorative! Really brightens my skin and overall skin tone. Fine lines are diminished. I use this at night. After I apply it and wait about 5 minutes, I also add Perricone's Evening Repair cream. The two together are incredible! I have been using these products for over 18 years! I don't look my age at all!

Karen B

Oceanside, Calif.


This one tips the scales


I have been using multiple Perricone products for a few years but decided to try this concentrated treatment recently. I have noticed a big difference in my crows feet and more smoothness around my eyes in general. My skin truly looks refreshed and radiant in just a few days using this along with the High Potency and other products including the DMEA pads. Have had 3 people in the last week tell me I don't look my age and I feel more confident about the way my eyes look. I am looking forward to more benefits after continued use!




Brightening Overnight Treatment

4.9 105


  • You Might Also Like
  • Recently Viewed
  • Related Prescription
Ask A Skincare Specialist

We want you to be 100% satisfied with your purchase, and stand by the quality of our products. Should you for any reason be unhappy with your purchase we will promptly issue a refund to your credit card or exchange an unsatisfactory product for another one. Please see returns & exchanges for details on how to process.

Highly trained Perricone MD experts ready to assist you. Speak with a consultant today

Shipping & Returns

At Perricone MD, we offer complimentary standard U.S. shipping and a number of flat fee-based domestic and international options. Simply select the appropriate shipping option for domestic or international delivery during checkout.

Should you for any reason be unhappy with your purchase, upon product return we will issue a refund to your credit card or exchange an unsatisfactory product for an alternative item.

Complimentary Samples

All orders include a complimentary choice of three sample packettes.

Find out more about PerriconeMD.com's variety of complimentary services.

Learn More