#5705

Acyl-Glutathione Deep Crease Serum

Acyl-Glutathione Deep Crease Serum - Perricone MD
  • Acyl-Glutathione Deep Crease Serum

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Acyl-Glutathione Deep Crease Serum - Perricone MD
Formulated with Dr. Perricone’s patented Acyl-Glutathione, this powerful anti-aging treatment is designed to address visible expression lines and creases that appear from repetitive facial movements to help achieve a more youthful looking appearance. Read More
$89.99 80.99
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Additional Information

Product Details

What It Is

Formulated with Dr. Perricone’s patented Acyl-Glutathione, this powerful anti-aging treatment is designed to address visible expression lines and creases that appear from repetitive facial movements. Over time, these engraved imperfections appear instantly smoothed, making creases appear shallower and erasing the look of furrow creases along the forehead, squinting creases and feathery lines along the lips to help achieve a more youthful looking appearance.

What It Does
  • Softens the look of facial lines from daily repetitive movements.
  • Visibly improves etched creases making them appear more shallow.
  • Minimizes the appearance of skin imperfections and imparts a beautiful radiance.
What To Expect

Due to the science and compounds used in our products the feel and scent may vary.

Texture

Serum

Consistency

Lightweight

Scent

Natural, Aromatic

Key Sciences

Acyl-Glutathione: The Master Antioxidant

Comprised of three amino acids, Glutathione is the body's main antioxidant and helps to reduce the look of deep creases and improve fragile skinby protecting, repairing and detoxifying. Fat-soluble for maximum stability and penetration.

Neuropeptides: Uniting Surface Cells to Fight Wrinkles

Powerful, protein-like building blocks offer the ultimate visible antidote to wrinkles, sagging, dullness, and discoloration. Neuropeptides encourage surface skin cells to work together via a unique chemical structure.

Acyl-Glutathione Deep Crease Serum Science

Ingredients

Acyl-Glutathione: The Master Antioxidant

Comprised of three amino acids, Glutathione is the body's main antioxidant and helps to reduce the look of deep creases and improve fragile skinby protecting, repairing and detoxifying. Fat-soluble for maximum stability and penetration.

Neuropeptides: Uniting Surface Cells to Fight Wrinkles

Powerful, protein-like building blocks offer the ultimate visible antidote to wrinkles, sagging, dullness, and discoloration. Neuropeptides encourage surface skin cells to work together via a unique chemical structure.

Ingredients

Water/Aqua/Eau, Glycerin, Tetrahexyldecyl Ascorbate, S-Palmitoylglutathione, Isopropyl Palmitate, Squalane, Butylene Glycol, Cyclopentasiloxane, Cetearyl Alcohol, Glycolic Acid, Glyceryl Stearate, PEG-100 Stearate, Dimethicone, Dimethyl MEA, Cyclohexasiloxane, Ceteareth-20, Fragrance/Parfum, Phenoxyethanol, Zinc Gluconate, Magnesium Aspartate, Caprylyl Glycol, Phosphatidylcholine, Disodium EDTA, Citric Acid, Docosahexaenoic Acid, Sorbic Acid, Linalool, Copper Gluconate, Tetrapeptide-21, Citronellol, Sodium Hyaluronate, Geraniol, Limonene, Acetyl Hexapeptide-8, Pentapeptide-18, Citral.

Application

Application

Dr. Perricone recommends smoothing onto a cleansed face in the morning, paying special attention to visible expression lines and creases. Follow with a Perricone MD moisturizer.

Application Process

Area

Face

Amount

1 - 2 Pumps

Frequency

1x / Day

Duration

8 Weeks

  1. Dispense 1 to 2 pumps onto fingertips.
  2. Smooth onto face, paying special attention to visible expression lines and creases.
  3. Use in the morning.
  4. Follow with a Perricone MD moisturizer.

Q&A

Hello. Does this product actually treat laugh lines or is it a temporary fix l? Will results stop once you stop using it? And how would i incorporate this if I use retin a at night? Thank you!

Melissa

Good question. The Acyl-Deep Crease Serum is an amazing daily spot treatment to be used for laugh lines, crows feet, the "elevens" and forehead area. Over time you will see the appearance of fine lines diminish. You can use day and night under your Retin A or just use in the morning.

Perricone MD Skincare Specialist

What is the percentage of glycolic acid in this product?

Ghotsibi

Good question! There is a little over 2% of glycolic acid in the Acyl-Glutathione Deep Crease Serum. Have a nice day!

Perricone MD Customer Care Specialist

Hello, Would I apply Acyl-Glutathione Deep crease Serum before or after Cold Plasma? And then apply Acyl-Glutathione Creme on top and them the final moisturiser( Neuropepeptide Firming moisturiser) Thank you

Budde

Great question! There are five steps to following the Perricone regime and they are: 1a. Cleanser 1b. Treatment Mask 2. Toner or Serum 3. Exfoliant 4. Treatment 5. Moisturizer The Acy-Glutathione Deep Crease Serum (Step 2) should be applied first then apply the Cold Plasma (Step 4), follow with the Acyl-Glutathione cream (Step 4) and the moisturizer (NP Firming Moisturizer) (Step 5) should always be applied last. Have a nice day!

Perricone MD Customer Care Specialist

I am going to buy acyl-glutathione deep crease serum but wonder if I can use it with the concentrated restorative cream at night or should I rotate using them every other night? I break out with the face firming moisturizer so I use no moisturizer. Any suggestions for that?

Kat

Thank you for your interest in Dr. Perricone's products. All of Dr. Perricone's products can be used together and it is perfectly fine to use both the Acyl-Glutathione Deep Crease Serum and the Concentrated Restorative Cream daily or every other day; which ever you prefer. Since you are unable to use the Face Finishing Moisturizer I recommend the Hypoallergenic Nourishing Moisturizer from Dr. Perricone's sensitive skin care line. Have a nice day!

Perricone MD Skincare Specialist

Hello , I am 22 years old and i lost over 50 lbs recently and im starting to see Jowls or Marionettes around my smile....is this product good for that? Or should I try another Perricone MD product?

Angie

Great question! Yes, the Acyl-Glutathione Deep Crease Serum will definitely address the smile lines and expression lines. Acyl-Glutathione Deep Crease Serum is a powerful anti-aging treatment designed to address expression lines and creases that appear from repetitive facial movements. Upon first application, these engraved imperfections appear instantly smoothed, making creases appear shallower and erasing the look of furrow creases along the forehead, squinting creases and feathery lines along the lips. Combined with its illuminating effect, this anti-aging serum is the ideal non-invasive alternative to help achieve a more youthful looking appearance.

Perricone MD Skincare Specialist

I have A-G deep crease serum, vit c ester 15,nueropeptide firming moisturizer, chia oil, chloroplasma and blue plasma. Kindly guide me how to use them. Also what r ur most powerful anti aging products. I'm 53 years and have droopy mouth corners, droopy eyelids. Thanks

r

Thank you for contacting Perricone MD. There are five steps to following the Perricone regime and they are: 1. Cleanser 2. Toner or Serum 3. Exfoliant 4. Treatment 5. Moisturizer Please see Application Protocol below: AM PRODUCTS PM PRODUCTS Cleanser Cleanser Chloro Plasma (2-3 times per week) Blue Plasma Acyl-Glutathione Deep Crease Serum Acyl-Glutathione Deep Crease NP Firming Moisturizer/chia serum NP Firming Moisturizer/chia serum The Chia Serum can be mixed with Neuropeptide Firming Moisturizer to provide additional moisture, or it can be used alone without moisturizer. I hope this is helpful.

Perricone MD Skincare Specialist

Does this go before Cold Plasma or after? Does this go before Vitamin C Serum? What order do Cold Plasma, Hyalo, Vitamin C Serum, and Acyl-Glutathione go in? Please do not advise me to the protocol page because it's not been helpful thus far.

fit3two

Thank you for contacting Perricone MD. There are five steps to following the Perricone regime and they are: 1. Cleanser 2. Toner or Serum 3. Exfoliant - (PM ONLY) 4. Treatment 5. Moisturizer The Acyl-Glutathione Deep Crease Serum (Step 2) for both AM & PM application. The Cold Plasma (Step 4) treatment is always the very first Perricone treatment applied both AM & PM. Vitamin C Ester Serum (Step 2) this is an AM serum and since you are also using the Acyl-Glutathione Deep Crease serum I recommend alternating, Use Vitamin C Serum in the AM and the Acyl-serum in the PM. Acyl-Glutathione (Step 4) treatment should be applied AM & PM after the Cold Plasma. Hyalo Plasma (Step 4) treatment should be applied after the Acyl-Glutathione both AM & PM. A moisturizer should always follow last. We also have an Application Protocol Sheet listed on our website: www.perriconemd.com; simply click at the top of the page on Customer Service, and to the left you will see a drop down menu, click on "Application Protocol". I hope this is helpful.

Perricone MD Skincare Specialist

I bought the Acyl-glutathione Deep Crease serum and it really works,but I get a TERRIBLE headache on my forehead after I use it. I mean blistering headache,I was wondering if this has happened before andwhat in it would cause this. I can't use the product anymore,I can't function if I do.Too bad, I love the results.

Julie

Thank you for contacting Perricone MD. We regret to hear of your experience although we have never received this type of complaint or heard of this occurring after using the Acyl-Glutathione Deep Crease Serum. Most people do not have any problem using Dr. Perricone's products, but there unfortunately is no list of ingredients that can be guaranteed to not disagree. Persons who have sensitive's should pay careful attention to what they use on their skin. It is virtually impossible to know if, when, or how anyone will react to any cosmetic. I recommend discontinuing usage of this product and returning for a refund. We have a variety of products that will address your concerns that contain different ingredients and I recommend calling our Customer Service Department (888-823-7837) and requesting a Skin Care Consultation,. I hope this is helpful.

Perricone MD Skincare Specialist

I am trying to decide whether I want the Acyl-Glutathione Deep Crease Serum v. the Acyl-Gluthathione. I use the A-G Eye Serum and I love it, I want to use the A-G on my face, but I don't know if I should get the serum or the other A-G product which I assume is also a treatment product and not a moisturizer. Please help as I am not sure what the difference is between those two products. Should they all be used together? Thank you!

Katina

Thank you for contacting Perricone MD. There are five steps to following the Perricone regime and they are: 1. Cleanser 2. Toner or Serum 3. Exfoliant 4. Treatment 5. Moisturizer The Acyl-Glutathione Deep Crease Serum (Step 2) is a serum and the Acyl-Glutathione (Step 4) is the treatment. If you are only able to purchase one I recommend the Acyl-Glutathione cream which is a powerful treatment that diminishes expression lines, wrinkles and creases. This treatment is applied both AM & PM and a moisturizer should always follow last. I hope this is helpful.

Perricone MD Skincare Specialist

Hi, I'm using Amine Facelift in AM and High Potency Evening Repair at bedtime. In the AM prior to putting on makeup, can Acyl-Glutathione Deep Crease Serum be used BEFORE OR AFTER the Amine Facelift to help diminish lines, OR should it NOT be combined with Amine Facelift at all?

nu

Great question! The Acyl-Glutathione Deep Crease Serum should be used before your High Potency Amine Face Lift during the day, and before the High Potency Evening Repair at night.

 

Reviews

Reviews

Not great

3

I do not see any improvement with this Serum. Also, it is very expensive

Sandy

New Jersey

false

No Evidence of Any Improvement

1

After over two weeks of application morning and evening, I see no evidence that wrinkles are fading, or any other effect.

CLW-G

NYC

false

Love it

4

Love this product! It does take time for you to see the true effects, but it's worth every penny!

JD

Jackson, MS

true

I would not buy again

1

I was using this under my daily cream, it does not hide the creases at all, not happy about that. Also the push top always spurts it all over. I like the daily cream.

dont have one

NY

false

No difference

1

It may be too soo but I see no change.

Phillygirl

Concord NC

false

Delicate Effectiveness

5

Product doesn't behave like a wrinkle " filler" but does soften fine lines without clogging pores or Creating a dry area where applied .

Alex

Wakefield RI

true

i really haven't tried this long enough.

4

I have been using this only about 10 days. I can't really tell if it will make my deep wrinkles improve, but I think I am seeing an improvement.

Sara

Pittsburgh

true

One of the BEST

5

Of all the serums including others by Perricone This is a wonderful addition that promises and delivers great results

Alex

Wakefield RI

true

I like the product but...

4

The pump needs some work. It sticks, then dispenses too much serum. I've had the same problem with the eyelid serum as well. I do feel like this serum helps my laugh lines.

Sweak

Illinois

true

I will continue to use

3

The product is light but penetrates slowly. I would like to have seen results quicker but I just started using about a month ago so will give it more time

Christine

Hoboken NJ

false

Acyl-Glutathione Deep Crease Serum

3.6 50

68.1

 
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