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Prebiotic Acne Therapy 90-Day Regimen Duo
What It Is
Perricone MD Acne Relief Prebiotic Acne Therapy is a simple, comprehensive system that works with your surface skin’s natural microbiome to safely, gently & effectively treat & prevent the most troublesome acne, while restoring & maintaining a healthy skin balance, for clearer, blemish-free skin. This powerful 2-step regimen is clinically proven to be non-irritating & will not strip or over-dry skin.
Gentle & Soothing Cleanser (6 fl oz / 177 mL)
Step 1 in your regimen. Use both day & night for fighting acne-causing bacteria. The non-foaming formula thoroughly cleanses, reduces excess oil, unclogs pores, removes dead skin cells & eliminates debris without irritating sensitive, acne-prone skin. Ultra-fine sucrose supports a healthy surface skin microbiome, yet rinses off quickly & easily, while squalane hydrates without making skin look or feel greasy.
Calming Treatment & Hydrator (2 fl oz / 59 mL)
Step 2 in your day or morning regimen after cleansing. This lightweight lotion glides onto skin to gently kill acne-causing bacteria, while nourishing with essential hydration. Lactic & succinic acids support a healthy surface skin microbiome for a clearer, more radiant complexion, while citrulline & squalane fight irritation, nourish, hydrate, soothe & visibly reduce redness.
Retinol Treatment & Moisturizer (2 fl oz / 59 mL)
Step 2 in your night regimen after cleansing. The lightweight yet nourishing formula absorbs instantly to control excess oil & helps to heal blemishes while you sleep without over-drying the skin. The powerful combination of retinol, citrulline & niacinamide helps to accelerate surface skin exfoliation & renewal, visibly calm skin & reduce redness, while gently & visibly erasing imperfections overnight.
What To Expect
Understand the science and benefits behind creating a healthy microbiome and balanced skin.
The science behind Acne Relief is our prebiotic approach, a system that adapts to your skin’s unique microbiome to target troublesome acne. Using naturally occurring prebiotics, Acne Relief helps your skin fight back against acne without disrupting its natural balance. The result? An effective defense against acne-causing bacteria that promotes a clear, blemish-free complexion.
Below are some of the key ingredients in Acne Relief behind our prebiotic approach:
Sucrose is made from ultra-fine sugar and is a mild exfoliant that helps unclog pores and remove excess dirt and oil without over-drying or stripping skin. Sucrose helps support a healthy skin microbiome by encouraging good bacteria. It rinses off quickly and easily, making it ideal for gentle yet effective cleansing.
Citrulline, first discovered in watermelon, is an alpha-amino acid that visibly calms skin for a clearer, more even-looking complexion. Nourishing and soothing, it is an ideal way to counteract the drying effect of anti-acne ingredients.
Lactic & Succinic Acids are short chain fatty acids help quickly shrink blemishes by working alongside salicylic acid to attack acne-causing bacteria and encourage good bacteria necessary for a healthy microbiome. They also provide gentle yet effective exfoliation for smoother, more even-looking skin.
Niacinamide, also known as Vitamin B3, is found in foods such as tomatoes. This skin-clearing powerhouse helps to gently and visibly erase imperfections, unclog oily pores, and minimize the redness and uneven tone that can be left behind after breakouts by improving skin’s moisture barrier.
Squalane is found naturally in the human body but also can be derived from olive oil. It hydrates skin without making it look or feel greasy. This lightweight hydration is ideal for oil and acne prone skin as it helps maintain optimal hydration without clogging pores or causing blemishes.
Salicylic Acid is a beta-hydroxy acid and is considered the best non-prescription treatment for acne and oil-prone skin. It quickly and effectively exfoliates and removes dead skin which can clog pores and cause breakouts. Because it is oil-soluble, salicylic acid is easily absorbed for targeted, more effective treatment.
Retinol is and ultra-powerful, non-prescription Vitamin-A derivative that helps prevent breakouts by unclogging pores and accelerating surface skin exfoliation and renewal. Unique slow-release carrier system helps preserve this unstable ingredient and calm skin.
Gentle & Smoothing Cleanser
Active ingredient: Salicylic Acid 2.0%. Inactive Ingredients: Glycerin, Sodium Cocoyl Isethionate, Ethylhexyl Palmitate, Silica Cetyl Sil- ylate, Sucrose, Squalane, Polyacrylamide, Water/ Aqua/Eau, Caprylyl Glycol, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol
Calming Treatment & Hydrator
Active ingredient: Salicylic Acid 0.5%. Inactive Ingredients: Water/Aqua/Eau, SD Alco- hol 40-B, Glycerin, C12-15 Alkyl Lactate, PVP, Di- methicone, Polysorbate 20, Citrulline, Squalane, Lactic Acid, Succinic Acid, Polyacrylamide, Dimeth- icone/Vinyl Dimethicone Crosspolymer, C13-14 Isoparaffin, Laureth-7, Phenoxyethanol, Sodium Benzoate, Potassium Sorbate
Retinol Treatment & Moisturizer
Active ingredient: Salicylic Acid 0.5%. Inactive Ingredients: Water/Aqua/Eau, SD Alcohol 40-B, Glycerin, Dicaprylyl Ether, Niacinamide, Cit- rulline, Arginine, Methyl Gluceth-20, Cetearyl Alco- hol, Carbomer, Xanthan Gum, Tocopheryl Acetate, Retinol, Citric Acid, Sodium Hydroxide, Disodium EDTA, PEG-20 Methyl Glucose Sesquistearate, PEG-100 Stearate, Glyceryl Stearate, Methyl Glu- cose Sesquistearate, Polysorbate 20, Phenoxy- ethanol, Sodium Benzoate, Potassium Sorbate
Gentle & Smoothing Cleanser - Step 1: Day & Night
Lather a quarter-sized amount in hands & gently massage onto damp skin. Rinse thoroughly with warm water. For best results, follow with ACNE RELIEF Calming Treatment & Hydrator in the morning & ACNE RELIEF Retinol Treatment & Moisturizer in the evening. If bothersome dryness or peeling occurs, reduce application to once a day or every other day.
Calming Treatment & Hydrator - Step 2: Day
Clean the skin thoroughly before applying this product. Shake well. Apply a thin, even layer to skin in the morning. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser. Cover the entire affected area with a thin layer one to three times daily. If bothersome dryness or peeling occurs, reduce application to once a day or every other day.
Retinol Treatment & Moisturizer - Step 2: Night
Clean the skin thoroughly before applying this product. Shake well. Apply a thin, even layer to skin in the evening. For best results, use after cleansing with ACNE RELIEF Gentle & Soothing Cleanser. Cover the entire affected area with a thin layer one to three times daily. Because excessive drying of the skin may occur, start with one application daily, then gradually increase to two or three times daily if needed or as directed by a doctor. If bothersome dryness or peeling occurs, reduce application to once a day or every other day.