Cold Plasma Anti-Aging Face Treatment

(934) Read Reviews
Cold Plasma Anti-Aging Face Treatment - Perricone MD
  • Cold Plasma Anti-Aging Face Treatment
  • Cold-Plasma-ReLaunch1080


Cold Plasma Anti-Aging Face Treatment - Perricone MD
(934) Read Reviews
Award-winning, patented technology powers this comprehensive anti-aging treatment, delivering dramatic, personal results for visibly smoother, firmer, radiant-looking skin. Read More
$149.00 134.10
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Product Details

What It Is

This comprehensive anti-aging treatment, ideal for all skin types, delivers powerful ingredients, precise technology and personal results for visibly smoother, firmer, radiant-looking skin.

Dr. Perricone’s proprietary Liquid Crystal Delivery System is what makes the Cold Plasma difference. This award-winning technology is the culmination of 5 years of research and 4 patents and effectively transports potent ingredients to where your skin needs it most for dramatic results. The most visible signs of aging are addressed; diminishing the appearance of fine lines, wrinkles, redness and discoloration and improving firmness, elasticity and radiance.

What It Does
  • Fights the most stubborn signs of aging: fine lines, wrinkles, discoloration and redness, loss of firmness and elasticity, enlarged-looking pores, rough texture.
  • Dr. Perricone’s proprietary Liquid Crystal Delivery System promotes optimal delivery of potent anti-aging ingredients for visibly dramatic, personal results.
  • Delivers the natural, rested and radiant appearance of healthy-looking, youthful skin.
  • Formulated WITHOUT parabens, sulfates, synthetic fragrances or synthetic dyes.
What To Expect

Our commitment to formulation integrity and effectiveness means that certain scents cannot be masked, but should dissipate quickly after application. Cold Plasma has no added fragrance.


Translucent cream transforms into lightweight serum


Lightweight, fast-absorbing


Our products are formulated with high quality ingredients, some having natural scents.


DMAE: Instant Firming

Naturally produced by the human brain, DMAE helps visibly lift sagging skin over time. Easily and quickly absorbed, it visibly plumps skin to help support skin's surface and protect against drying environmental aggressors.

Liquid Crystal Delivery System

An award-winning technology from Dr. Perricone that ensures the delivery of optimal nutrients to where skin needs it the most for maximum benefits.


Aqua (Water), Glycerin, Tetrahexyldecyl Ascorbate, Phosphatidylcholine, Isopropyl Palmitate, L-Tyrosine, Butylene Glycol, Glyceryl Stearate, PEG-100 Stearate, Cetearyl Alcohol, Oligopeptide-17, Ceteareth-20, Magnesium Aspartate, Zinc Gluconate, Dimethyl MEA (DMAE), Docosahexaenoic Acid, Ascorbyl Palmitate, Phenoxyethanol, Dimethicone, Caprylyl Glycol, Glycolic Acid, Retinyl Palmitate, Saccaromyces Ferment, Elaeis Guineensis (Palm) Oil, Carbomer, Disodium EDTA, Tocotrienols, Copper Gluconate, Polysorbate 20, Sorbic Acid, Tocopherol, Sodium Hyaluronate, Acetyl Hexapeptide-8, Palmitoyl Oligopeptide, Astaxanthin, Palmitoyl Tetrapeptide-3



To achieve optimal results, Dr. Perricone recommends always starting with Cold Plasma Anti-Aging Face Treatment as the first step. Apply a pearl-sized amount onto cleansed skin morning and evening. If needed, follow with a Perricone MD targeted treatment and moisturizer.

Application Process




Pearl-Sized Amount


2x's / Day


8 Weeks

  1. After cleansing skin, use fingertips to apply all over the face in the morning and evening.
  2. Follow with a Perricone MD treatment and moisturizer.


Is this vegan?


Cold Plasma contains L-Tyrosine and most sources in the world of L-Tyrosine are from duck feathers. While this is not an animal meat source, some people consider feathers to be an animal byproduct. If this is a concern of yours we recommend the newer Cold Plasma Plus Face without L-Tyrosine.


I had the just purchased a jar of the Cold Plasma Sub-D and it was in the trunk during a 87 degree day for eight hours. Was the cream adversely affected by the heat?


Hello, the product should be fine. Dr. Perricone does many extreme heat/cold testing for our products.


I have multiple products and need to know in which order to apply them, which are better to use AM or PM, combination for winter vs summer, etc. the products I have are as follows: Cold plasma plus face Cold plasma sub d Neuropeptide facial conformer Neuropeptide facial cream Neuropeptide night cream Face finishing moisturizer Neuropeptide firming moisturizer All of the products are great and I want to maximize the benefits.


Hello, we recommend during the day use Cold Plasma Plus face, the the NP Faicial Conformer, the Neuropeptide Facial Cream and your moisturizer. At night after cleansing, use the Cold Plasma Plus Face, the Neuropeptide Night cream and your moisturizer. Both day and night use the Cold Plasma Sub D for your neck. Don't forget an eye cream.


What is the difference between Cold plasma anti aging face and Cold plasma plus face other than packaging?


Cold Plasma Plus Face is the new formulated version of Cold Plasma. Dr. Perricone has added some new peptides and Omegas to Cold Plasma Plus Face. It has a more luxurious hydrating texture.


I just received the Perricone Power Treatment Essentials kit which includes the Cold Plasma Sub-d, Face Finishing moisturizer and Neuropeptide Night Cream. It was so hot outside that all of the products arrived very runny. Will this affect the performance of these products?


They should return to a consistent texture after they've cooled down. They are fairly resistant to temperature fluctuations. If they have separated into water and lumps you may want to contact QVC for an exchange.

might be a stupid question but its called cold plasma but its warm and runny. Does it needs to be refrigerated/


Thank your question and it is a very good questions indeed. Cold Plasma serum is a water based serum, the texture is supposed to be very light. You don't have to refrigerate it but if you would like a cooling effect then you diffidently can do that.

the sale on Cold Plasma for $135- is this 1, 2, or 3 fl oz?

Julie Kay

Hi there. This is for the 1 ounce size Cold Plasma - SRP of $162.

Why does the Cold Plasma Sub D smell like fish?


Hi there. Perricone MD products are formulated with the highest quality ingredients, some having natural medicinal scents. Our commitment to formulation integrity and maximum effectiveness means that sometimes the scents cannot be masked, but should dissipate after application. We use no fragrance in our products as this could compromise the efficacy and/or fragrance is oftentimes the cause of irritation. Hope this helps.. The malodorous odor will be gone in a flash; the visible results last much longer! :)

I have blue plasma and cold plasma. Which one should I use before the other?


Thank you for contacting Perricone MD. There are five steps to following the Perricone regime and they are: 1. Cleanser 2. Toner or Serum 3. Exfoliant - (PM ONLY) 4. Treatment 5. Moisturizer The Blue Plasma (Step 3) is a PM exfoliant and should be applied before the Cold Plasma (Step 4) and a moisturizer should always follow last. Have a great day!

Perricone MD Customer Care Specialist

Is this safe to use if you are trying to conceive and during pregnancy?

Trying to Conceive

Thank you for your interest in Dr. Perricone's products. Dr. Perricone's products have not been tested on women who are pregnant or nursing. Although Dr. Perricone does not foresee any problems with this, it is important that you know that they have not been tested. If you have any concerns about product usage, we recommend that you discuss this with your physician. We do list our ingredients on our product packaging and on our website, so we recommend checking these ingredients with your personal physician. Have a nice day!

Perricone MD Customer Care Specialist




Not impressed


From other reviews, I expected not to like the smell of this product. But, it has a thinner consistency than expected and basically hasn't produced any better results than a drugstore anti-aging lotion. The jar labeling seems cheap. And, there should be an inner seal between the cream and the inside of lid. When I first opened the jar, cream slopped out onto my bathroom counter and hand.




i love how my skin feels


i never held out much hope that skincare products would do what they said, but then i tried hyaloplasma...and was sold on perricone products...then i tried cold plasma and i am in love with it. my skin feels tight when i use it, looks fresh and smooth and i adore it. i have been using perricone for 5-6 years now and at 61, most people think i am 45...yippppeeeeee!


philadelphia, pa


Cold Plasmazing!


Improved skin texture, pore size, softened lines and added brightness. Moisturizing and beneficial, a must for skin health.


New York




I started using the cream about 2-3 weeks ago. I have noticed smoother skin tone. I haven't really noticed a difference in wrinkles. Although, I do not have too many wrinkles at my age. I will continue to use.

Always updating



High Performance


One of the best Perricone products I have: and I have a lot!! Texture, feel and results are all as promised in the description Very pleased !


Wakefield RI


Can't get past the smell


I can't determine if the product works because I haven't been able to leave it on my face long enough. I've tried numerous times. It has the smell of dead Fish! Unfortunately the odor is so strong that I have to wash my face right after I put it on. I had hope the odor would go away after I put it on, didn't happen.




I would buy this product again


Discoloration really disappeared although not right away but it gradually gone after about 6 to 8 weeks : )


Mission Viejo, CA


so far so good


So far seems to be working well - not fond of scent - guess it has been reformulated to be odorless - must be why it was on sale when I bought a couple weeks ago.

Auntie B

Portland, OR



I really love using it on my face and neck.


Fairmount in


I would buy this product again


When I first opened cold plasma to spot test it, I thought it smelled very bad. I was disappointed with the smell, but the product is actually great. I have tested different products over the past 2 years & this is the best results I have experienced. I noticed a reduction in my pores and fine lines/wrinkles. The only con other than the smell is the price is high. I would definitely buy this again. It works.


Paragould, AR


Cold Plasma Anti-Aging Face Treatment

4.3 934


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