#5703

Acyl-Glutathione

Acyl-Glutathione

$185.00
(133) Read Reviews
Acyl-Glutathione
Formulated with Dr. Perricone’s patented Acyl-Glutathione, this night treatment is specifically designed to minimize the look of creases while improving the appearance of thinner, more fragile-looking skin texture for overall visibly younger skin.
(133) Read Reviews

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    Product Details
    What It Is

    Formulated with Dr. Perricone’s patented Acyl-Glutathione, this night treatment is specifically designed to minimize the look of lines and creases while improving the appearance of thinner, more fragile-looking skin texture for overall visibly younger skin.

    What It Does
    • Diminishes the look of creases along targeted areas of the face.
    • Enhances the appearance of skin's elasticity and resilience.
    • Visibly improves fragile skin texture while imparting the radiance of youthful skin.
    What To Expect

    Due to the science and compounds used in our products the feel and scent may vary.

    Texture

    Lotion

    Consistency

    Lightweight

    Scent

    Natural, Aromatic

    Key Sciences

    DMAE

    Scientifically formulated to help firm and tone the appearance of skin.

    Acyl-Glutathione

    Scientifically formulated to minimize the appearance of lines and creases while improving skin vitality.

    Acyl-Glutathione Science
    Ingredients
    DMAE

    A powerful ingredient in the fight against loss of skin firmness, it delivers a lifted, contoured, more sculpted appearance.

    Acyl-Glutathione

    Replenishes the body's master antioxidant to minimize the appearance of creases and other signs of accelerated skin aging.

    Ingredients

    Aqua (Water), Isopropyl Palmitate, Tetrahexyldecyl Ascorbate, Cetearyl Alcohol, Phosphatidylcholine, S-Palmitoylglutathione, L-Tyrosine, Dimethyl MEA (DMAE), Glyceryl Stearate, PEG-100 Stearate, Ceteareth-20, Glycolic Acid, Oligopeptide-17, Oligopeptide-49, Squalane, Butyrospermum Parkii (Shea) Butter, Limnanthes Alba (Meadowfoam) Seed Oil, Docosahexaenoic Acid, Dimethicone, Sesamum Indicum (Sesame) Seed Oil, Glycerin, Magnesium Aspartate, Zinc Gluconate, Phenoxyethanol, Caprylyl Glycol, Parfum (Fragrance), Propylene Glycol, Disodium EDTA, Hydrolyzed Glycosaminoglycans, Elaeis Guineensis (Palm) Oil, Citric Acid, Tocotrienols, Copper Gluconate, Sorbic Acid, Tocopherol, Ascorbyl Palmitate, Thioctic Acid (Alpha-Lipoic Acid), Linalool

    Application

    Application

    Dr. Perricone recommends massaging onto a cleansed face and neck in the evening. Follow with a Perricone MD moisturizer.

    Application Process

    Area

    Face and Neck

    Amount

    Pearl-Sized Amount

    Frequency

    1x / Day

    Duration

    12 Weeks

    1. Dispense 1 pump per eye onto fingertips.
    2. Apply directly to the eye lid up, moving up to the eye brow bone in gentle patting motions.
    3. Apply along crows feet and lower contours of the eyes.
    4. Use in the morning and evening.
    5. Follow with a Perricone MD eye cream.
    Q&A

    Do you have questions about this product?

    Get answers from real customers and in-house experts with AnswerBox.

    20 Questions | 20 Answers
    Displaying questions 1-10Previous | Next »
    • Q:

      My a.m. face routine - intensive pore minimizer, blue plasma, cold plasma,high potency face lift and FF moisturizer. My p.m. face routine - serum prep, cold plasma, high potency evening repair and FF moisturizer. Would the AG cream be good to add to this routine, and if so at what step in the routines? Should it replace any of the products I currently use? Should this be applied to the whole face or just problem areas?
      Thank you!
      Asked on 4/8/2014 by TotalPerriconeConvert from Dayton, OH

      1 answer

      • Perricone MD Skincare Specialist

        A:

        Acyl-Glutathione is a phenomenal treatment that addresses the following concerns:• Severe skin dryness
        • Deeper set lines and wrinkles especially on targeted areas of the face
        • Thinner, more fragile looking skin
        • Extreme loss of elasticity leading to visible sagging appearance
        • Lack of energy and vitality on the skin leading to dullness

        If these are your concerns I recommend adding to your current regime. This treatment should be applied after the Cold Plasma both in the AM &PM, follow with other Perricone products and moisturizer is always last.

        Have a nice day!

        Answered on 4/8/2014 by Perricone MD Skincare Specialist from Perricone MD Customer Care
    • Q:

      How do you use it? How do you put it on?
      Asked on 4/6/2014 by The youn 58 year old. from Newark, Ca.

      1 answer

      • Perricone MD Skincare Specialist

        A:

        Dr. Perricone recommends first warming up a small amount of product between your hands to facilitate spread over the entire face. Slide the pads of the fingers from the center of the eyebrows towards the outside of the forehead.

        Then with the palms of the hand proceed over temples, cheekbones and sides of nose in a gentle patting motion. End by sweeping upwards from the neck to the chin and jawline. Apply morning and evening after make-up removal on well cleansed skin.

        Answered on 4/8/2014 by Perricone MD Skincare Specialist from Perricone MD Customer Care
    • Q:

      Hi. I'm 41 and starting to deal with 11 wrinkles, creases along the forehead and laughter lines. I recently bought the complete acyl-glutathione line (both serums and the AG). I also use Formula 15, Vitamin C Ester. What would be the best way to combine them for optimal and fast results? Should I alternate them? Thank you.
      Asked on 3/25/2014 by Margit from São Paulo, Brazil

      1 answer

      • Perricone MD Skincare Specialist

        A:

        It is not necessary to use both the Formula 15 and Acyl-Glutathione Cream in the AM; so I recommend alternating. Since Formula 15 is an AM treatment use the serum, then the Formula 15 and a moisturizer is always applied last.

        In the PM apply Acyl-Glutathione Deep Crease Serum, Vitamin C Ester 15, Acyl-Glutathione Cream and moisturizer last.

        I hope this is helpful.

        Answered on 4/1/2014 by Perricone MD Skincare Specialist from Perricone MD Customer Care
    • Q:

      what is the expiry date for this
      Asked on 3/14/2014 by hi

      1 answer

      • Perricone MD Skincare Specialist

        A:

        All of Dr. Perricone's products have a 2 year shelf life.

        Answered on 3/19/2014 by Perricone MD Customer Care
    • Q:

      do you use this at night on top of c-ester and or 15 or under. I uses them every other night and ovm in the morning
      Asked on 2/10/2014 by vicki from indialantic fl

      1 answer

      • Perricone MD Skincare Specialist

        A:

        The Vitamin C Ester 15 is a night time serum and should be applied after cleansing, then apply the Acyl-Glutathione and a moisturizer is always recommended last. If you are using an AM treatment that contains the vitamin c ester, such as the High Potency Amine Complex Face Lift, the Acyl-Glutathione is applied first then the HP Amine and a moisturizer last.

        Answered on 2/11/2014 by Perricone MD Skincare Specialist from Perricone MD Customer Care
    • Q:

      Received for a gift the cold plasma and the acrylic glutathione and I am not sure how to use or when. Can you assist me?
      Asked on 1/26/2014 by Jeanie from Oxford ga

      1 answer

      • Perricone MD Skincare Specialist

        A:

        Thank you for contacting Perricone MD.

        The Cold Plasma is always the very first treatment applied after cleansing and using either a serum or toner; then follow with the Acyl-Glutathione and Dr. Perricone recommends applying a moisturizer last over treatments; this should be done both AM and PM.

        I hope this is helpful.

        Answered on 1/29/2014 by Perricone MD Skincare Specialist from Perricone MD Customer Care
    • Q:

      Do I have to wait to apply acyl-glutathione after co;d plasma or do I aply immediately after cold plasma? Does photo plasma go right on after or again do I have to wait a bit and let the other absorb?
      Asked on 1/14/2014 by lynn from homer ,IL

      1 answer

      • Perricone MD Skincare Specialist

        A:

        Dr. Perricone's products absorb very quickly into the skin and it is not necessary to wait in between applications; the Acyl-Glutathione can be applied immediately after Cold Plasma. Photo Plasma is a moisturizer and it is always applied last. I hope this is helpful.

        Answered on 1/14/2014 by Perricone MD Skincare Specialist from Perricone MD Customer Care
    • Q:

      It can be used alone without a humidifier cream?
      Asked on 1/3/2014 by Tanya

      1 answer

      • Perricone MD Skincare Specialist

        A:

        The Acyl-Glutathione is considered a treatment so you would use a moisturizer after applying this product.

        Answered on 1/3/2014 by Perricone MD Customer Care
    • Q:

      does one need to use a moisture over this product?
      If so what one would be recommended?
      Asked on 12/27/2013 by justcarol from So CA

      1 answer

      • Perricone MD Skincare Specialist

        A:

        The Acyl-Glutathione is considered a treatment to be used twice per day. Perricone recommends using a moisturizer over the top. We have different moisturizers depending on your concerns and the age of your skin. You may view all of our moisturizers on www.perriconemd.com.

        Answered on 12/29/2013 by Perricone MD Customer Care
    • Q:

      How much of this cream do you need and do you apply it to bare face. Also, what other product do you use along with it or instead of in the Perricone line.
      Asked on 12/1/2013 by no nickname from Yorba Linda Ca

      1 answer

      • Perricone MD Skincare Specialist

        A:

        A dime size to nickel size amount should be plenty depending on the size and shape of your face. Acyl-Glutathione can be used with all of the PerriconeMD products.

        Answered on 12/10/2013 by PerriconeMD Customer Care
    Displaying questions 1-10Previous | Next »

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    Reviews

    Reviews

    REVIEW SNAPSHOT®

    by PowerReviews
    Perricone MDAcyl-Glutathione
     
    4.5

    (based on 133 reviews)

    Ratings Distribution

    • 5 Stars

       

      (105)

    • 4 Stars

       

      (13)

    • 3 Stars

       

      (3)

    • 2 Stars

       

      (1)

    • 1 Stars

       

      (11)

    91%

    of respondents would recommend this to a friend.

    Pros

    • Softens skin (6)
    • Non-greasy (5)
    • Absorbs quickly (4)
    • Smells great (4)
    • Easy to use (3)

    Cons

    • Pricey / poor value (5)
    • Price (3)
    • Pricey (3)

    Best Uses

    • Morning and evening (6)
    • Morning and night (3)
      • Reviewer Profile:
      • Brand buyer (4)

    Most Liked Positive Review

     

    Dramatic Great Results

    As a faithful user of most Dr Perricone's products, I was following the launch of Acyl-Glutathione with great interest and I was waiting impatiently for it to cross the Atlantic and to reach us...Read complete review

    As a faithful user of most Dr Perricone's products, I was following the launch of Acyl-Glutathione with great interest and I was waiting impatiently for it to cross the Atlantic and to reach us in the UK.
    As one of the very first users, I have refrained myself to write an immediate review documenting the dramatic and instant difference it has made to my skin. I wanted to see the developing benefits; so, I could give a more accurate and detailed review.
    For someone who is slightly over 50, I have a very good skin that I have looked after very well by following anti-inflammatory diets, excercise,and I have been using faithfully Dr Perricone's products.

    Acyl-Glutathione gave me an immediate radiance, a healthy glow, erased a few wrinkles on my forehead and to my utmost surprise had a lifting properties to it that was superior to the Neuropeptide's conformer, in my case.

    I use it morning and evening after cleansing with Nutritive cleanser.
    At first, I wanted to examine its power so I used it alone and only added the Face Finishing Moisturiser. I can assure you that these products together represent a marriage made in heaven.

    If you havent been using any Perricone's products these three products are a must.

    If you have been using other products, and all depends on what you have, this is a very suitable order for their applications:
    1. Cleansing
    2. Serum Prep (in my case) or your toner
    3. Cold plasma eye, Cold Plasma, and Cold Plasma Sub D
    4. Acyl-Glutathione
    5. Advanced Face Firming Activator or High Potency Face Amine Lift (I alternate during the day) and I use the Concentrated Restorative Cream in the evening application
    6. Face Finishing Moisturiser or the Neuropetide Moisturiser.

    Well done Dr Perricone and Thank you, again.

    VS

    Most Liked Negative Review

     

    Don't use if you have sensitive skin

    I'm 50 and have fair skin with very few wrinkles;however, I have noticed that since I have lost weight I have a lack of firmness around my mouth. I have used the...Read complete review

    I'm 50 and have fair skin with very few wrinkles;however, I have noticed that since I have lost weight I have a lack of firmness around my mouth. I have used the Dr. Perricone's eye C-Ester and firming lotion for the past year and I have liked those. So I thought I would give this product a chance. I've been using it for a week and have developed red, itchy skin, and a couple of bumps. My skin also has a burning sensation. So Dr. Perricone should note that this product should not be used on sensitive skin or on people who have Rosacea.

    Reviewed by 133 customers

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    (7 of 7 customers found this review helpful)

     
    5.0

    Perricone's Best Product

    By Mel

    from Philadelphia

    Verified Reviewer

    Pros

      Cons

        Best Uses

          Comments about Perricone MD Acyl-Glutathione:

          After the first application, I immeidately noticed an overall firmer appearance. After a month, my problem areas are firmer and tighter. My skin is not nearly as dull and dry as it was. I haven't noticed a difference in my '11 lines', but that is probably my fault as I squint too often. I have been using Perrione prodcuts for almost 10 years. This is, by far, the best treatment. I use it in the morning over Vitamin C Ester Serum and Hyaloplasma and follow with Deep Moisture Therapy. Because of the cost, I don't often use it at night. I geneally alternate between Formula 15 and OVM over Blue Plasma in the evening.

          • Was this a gift?:
          • No

          (18 of 18 customers found this review helpful)

           
          5.0

          ANOTHER GREAT PERRICONE PRODUCT

          By benni

          from sd

          About Me Brand Buyer

          Verified Reviewer

          Pros

          • Easy To Use
          • Evens Out Skin Tone
          • Improves Skin Texture
          • Minimizes Wrinkles
          • Non-Greasy
          • Noticeable Results

          Cons

            Best Uses

              Comments about Perricone MD Acyl-Glutathione:

              This is a great product. Not everything works for everyone and since they have a great return policy just try for yourself. I have found that it takes time I have used for several months. I myself almost sent back in the first month but held firm to my belief in the Perricone line and very glad I did. If your skin is allergic that does not mean the product is bad or wrong it just does not work with your body chemistry; try something else. Is it going to take all of your lines away; probably not. But it firms and adds smoothness to your skin. Wrinkles are sagging skin so if you give it the proper nutrients outside and inside you will see a difference. I have been working on getting my products down to a few power house must haves. This along with the Neuropeptides are a must in my daily skincare routine.

              (10 of 12 customers found this review helpful)

               
              5.0

              Look years younger

              By Gma Kathe

              from Newport Beach, CA

              About Me Brand Buyer

              Verified Reviewer

              Pros

              • Easy To Use
              • Improves Skin Texture
              • Minimizes Wrinkles
              • Non-Greasy
              • Noticeable Results

              Cons

                Best Uses

                • Deep Wrinkles
                • Fine Lines
                • Oily/Combination Skin
                • Sun Damage

                Comments about Perricone MD Acyl-Glutathione:

                This stuff is a miracle cream! Results appear almost from the first use, noticeable improvement in texture, reduction in pore size and acne scars. I was so impressed with this one $15.00 sample that I went out and bought the whole line of products. The 20 something at the doctors office said I looked 43; at 53 this made my week. Strongly recommend purchasing at any price.

                (8 of 13 customers found this review helpful)

                 
                1.0

                Acyl-Glutathione Product Review

                By The beach girl

                from Florida

                About Me Brand Buyer

                Pros

                • Easy To Use

                Cons

                • Irritates Skin
                • No Noticeable Results

                Best Uses

                • Deep Wrinkles

                Comments about Perricone MD Acyl-Glutathione:

                I am a 70 year old woman who until recently had very few visible lines. I suddenly noticed fine lines, deep wrinkles around my mouth, sagging, some sensitivity and small some bumps on my skin, primarily neck. I tried this product and have been using it at night with the gentle cleanser and a moisturizer for about a month. There is no visible improvement and I believe that the conditions actually worsened. I do not put it around my eyes but the skin from my brow to my upper cheekbone is bright red when I use this product.

                (11 of 11 customers found this review helpful)

                 
                5.0

                LOVE LOVE LOVE

                By Milli

                from Washington, DC

                Verified Reviewer

                Pros

                • Absorbs Quickly
                • Goes On Smoothly
                • Long Lasting
                • Not Greasy
                • Softens Skin

                Cons

                  Best Uses

                    Comments about Perricone MD Acyl-Glutathione:

                    I am 35 years old with 2 young kids and a busy household...I care about my skin and want to maintain it. I recently purchased this and have been using it at night only. I use cold plasma first and then this on top. My skin looks and feels amazing. My skin appears lifted, it feels more firm and lessens the appearance of my wrinkles. I use other products in the morning on top of my cold plasma but I think this product is better.

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